Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

Here, I introduce the concept of 'integrated organ immunity'to explain how the innate and
adaptive immune systems and non-haematopoietic cells can interact in tissues to generate …

Viral co-infections have been implicated in worsening tuberculosis (TB) and during the
COVID-19 pandemic, the global rate of TB-related deaths has increased for the first time in …

The observation of reduced COVID-19 incidence and severity in populations receiving
neonatal intradermal BCG vaccination vaccine raised the question of whether BCG can …

Abstract Vaccines such as Bacille Calmette–Guérin (BCG) can apparently defer dementia
onset with an efficacy better than all drugs known to date, as initially reported by Gofrit et …

The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2
infection is incompletely understood. Here we examine the roles of the prototypic pro-and …

ABSTRACT Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2) has resulted in substantial morbidity and mortality …

At the beginning of the COVID-19 pandemic those with underlying chronic lung conditions,
including tuberculosis (TB), were hypothesized to be at higher risk of severe COVID-19 …

The clinical treatment of patients with cancer who are also diagnosed with coronavirus
disease (COVID-19) has been a challenging issue since the outbreak of COVID-19 …

Cytokines, chemokines, and interferons are released in response to viral infection with the
ultimate aim of viral clearance. However, in SARS-CoV-2 infection, there is an imbalanced …