Nutraceuticals are defined as foods or their extracts that have a demonstrably positive effect
on human health. According to the decision of the European Food Safety Authority, this …

Cardiovascular diseases are the leading cause of death. The underlying pathophysiology is
largely contributed by an overactivation of the renin-angiotensin-aldosterone-system …

The causative role of inflammation in hypertension-related cardiovascular diseases is
evident and calls for development of specific immunomodulatory therapies. We tested the …

Hypertension, which is known as a silent killer, is the second leading cause of kidney failure
worldwide. Elevated blood pressure causes approximately 7.6 million deaths, which account …

Renin catalyzes the rate‐determining step in the renin–angiotensin–aldosterone system that
regulates mammalian blood pressure by converting angiotensinogen to angiotensin I (Ang …

Enzymatic hydrolysis of proteins from rice, soy, pea and wheat, with both chymotrypsin and
thermolysin, resulted in hydrolysates, which are efficient inhibitors of the angiotensin …

Rapeseed proteins are a rich source of bioactive peptides. LY, RALP and GHS were
previously identified from rapeseed protein hydrolysates as potent ACE and renin inhibiting …

Abstract Background Tryptophan (Trp) has been extensively studied for many years due to
its unique and multifaceted role in human health and diseases. Trp-rich oligopeptides …

The renin-angiotensin system (RAS) is involved in the development of left ventricular
hypertrophy (LVH) by which increases cardiac morbidity and mortality. Activation of mitogen …

Estrogen modulates adrenergic reactivity of macrovessels, resulting in weaker α-adrenergic
vasoconstriction in females than males. However, the mechanisms governing this important …