[HTML][HTML] The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis

SH Hoeboer, PJ van der Geest, D Nieboer… - Clinical Microbiology …, 2015 - Elsevier
The diagnostic use of procalcitonin for bacterial infections remains a matter of debate. Most
studies have used ambiguous outcome measures such as sepsis instead of infection. We …

Diagnostic and prognostic biomarkers of sepsis in critical care

S Kibe, K Adams, G Barlow - Journal of antimicrobial …, 2011 - academic.oup.com
Sepsis is a leading cause of mortality in critically ill patients. Delay in diagnosis and initiation
of antibiotics have been shown to increase mortality in this cohort. However, differentiating …

Role of cytokines as a double-edged sword in sepsis

H Chaudhry, J Zhou, YIN Zhong, MM Ali, F McGuire… - In vivo, 2013 - iv.iiarjournals.org
Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Biomarkers of inflammation and the etiology of sepsis

I Grondman, A Pirvu, A Riza, M Ioana… - Biochemical Society …, 2020 - portlandpress.com
Sepsis is characterized as a life-threatening organ dysfunction syndrome that is caused by a
dysregulated host response to infection. The main etiological causes of sepsis are bacterial …

Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis

EK Vouloumanou, E Plessa… - Intensive care …, 2011 - Springer
Purpose To assess the value of serum procalcitonin (PCT) for the differentiation between
patients with and without neonatal sepsis. Methods We systematically searched PubMed …

D-dimer is a significant prognostic factor in patients with suspected infection and sepsis

JR Rodelo, G De la Rosa, ML Valencia… - The American journal of …, 2012 - Elsevier
Purpose The aim of the study was to determine whether C-reactive protein (CRP),
procalcitonin (PCT), and d-dimer (DD) are markers of mortality in patients admitted to the …

Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency department

S Riedel, JH Melendez, AT An… - American journal of …, 2011 - academic.oup.com
Rapid diagnosis of bloodstream infections (BSIs) in the emergency department (ED) is
challenging, with turnaround times exceeding the timeline for rapid diagnosis. We studied …

Predictive value of procalcitonin decrease in patients with severe sepsis: a prospective observational study

S Karlsson, M Heikkinen, V Pettilä, S Alila, S Väisänen… - Critical Care, 2010 - Springer
Introduction This prospective study investigated the predictive value of procalcitonin (PCT)
for survival in 242 adult patients with severe sepsis and septic shock treated in intensive …

Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

DO Thomas-Rüddel, B Poidinger, M Kott, M Weiss… - Critical care, 2018 - Springer
Background This study aimed to evaluate the accuracy of procalcitonin (PCT) serum
concentrations to diagnose Gram-negative bacteremia and the association of PCT serum …

Procalcitonin levels in gram‐positive, gram‐negative, and fungal bloodstream infections

C Leli, M Ferranti, A Moretti, ZS Al Dhahab… - Disease …, 2015 - Wiley Online Library
Procalcitonin (PCT) can discriminate bacterial from viral systemic infections and true
bacteremia from contaminated blood cultures. The aim of this study was to evaluate PCT …