Genomic instability and genetic mutations can lead to exhibition of several cancer hallmarks
in affected cells such as sustained proliferative signaling, evasion of growth suppression …

The Metastatic progression of solid tumors, such as thyroid cancer is a complex process
which involves various factors. Current understanding on the role of epithelial …

Angioinvasion remains the important prognostic feature in papillary thyroid cancer (PTC)
patients. Literature data indicates several markers that may be associated with oxidative …

Immune system plays a key role in cancer prevention as well as in its initiation and
progression. During multistep development of tumors, cells must acquire the capability to …

Thyroid tumors are extremely heterogeneous varying from almost benign tumors with good
prognosis as papillary or follicular tumors, to the undifferentiated ones with severe …

Anaplastic thyroid carcinoma (ATC) is a rare and extremely aggressive type of thyroid
cancer, and the potential mechanisms involved in ATC progression remains unclarified. In …

Autoimmune thyroid disease is a complex and highly frequent disease, where a wide variety
of genetic, epigenetic and environmental factors (among others) come together and interact …

Thyroid cancer (TC) is the most frequent malignancy of the endocrine system. Apatinib, as
an anti-angiogenic agent, has been applied in the therapy of several cancers. However, the …

Papillary thyroid cancer (PTC) is the most prevalent endocrine tumor, and its incidence is
still increasing. The mechanisms of PTC dedifferentiation and malignant progression remain …

Long non-coding RNA LIFR-AS1 is low-expressed in many cancers, but its functions in
papillary thyroid carcinoma (PTC) were not defined and require further study. The …