Imaging structural and functional brain development in early childhood

JH Gilmore, RC Knickmeyer, W Gao - Nature Reviews Neuroscience, 2018 - nature.com
In humans, the period from term birth to∼ 2 years of age is characterized by rapid and
dynamic brain development and plays an important role in cognitive development and risk of …

Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

BRH Van den Bergh, MI van den Heuvel… - Neuroscience & …, 2020 - Elsevier
Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …

Pregnancy as a period of risk, adaptation, and resilience for mothers and infants

EP Davis, AJ Narayan - Development and psychopathology, 2020 - cambridge.org
The pregnancy period represents a unique window of opportunity to identify risks to both the
fetus and mother and to deter the intergenerational transmission of adversity and mental …

Prenatal stress: Effects on fetal and child brain development

A Lautarescu, MC Craig, V Glover - International review of neurobiology, 2020 - Elsevier
The impact of stress on brain health begins in the womb. Both animal and human studies
have found that prenatal maternal stress affects the brain and behavior of the offspring …

Treatment resistant depression: a multi-scale, systems biology approach

H Akil, J Gordon, R Hen, J Javitch, H Mayberg… - Neuroscience & …, 2018 - Elsevier
An estimated 50% of depressed patients are inadequately treated by available interventions.
Even with an eventual recovery, many patients require a trial and error approach, as there …

The cortisol switch between vulnerability and resilience

ER de Kloet, M Joëls - Molecular Psychiatry, 2024 - nature.com
In concert with neuropeptides and transmitters, the end products of the hypothalamus-
pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone …

Fetal origins of mental health: the developmental origins of health and disease hypothesis

KJ O'Donnell, MJ Meaney - American Journal of Psychiatry, 2017 - Am Psychiatric Assoc
The quality of fetal growth and development predicts the risk for a range of
noncommunicable, chronic illnesses. These observations form the basis of the …

Sex differences in anxiety and depression clinical perspectives

M Altemus, N Sarvaiya, CN Epperson - Frontiers in neuroendocrinology, 2014 - Elsevier
Sex differences are prominent in mood and anxiety disorders and may provide a window
into mechanisms of onset and maintenance of affective disturbances in both men and …

Developmental origins of health and disease: current knowledge and potential mechanisms

DJ Hoffman, RM Reynolds, DB Hardy - Nutrition reviews, 2017 - academic.oup.com
Epidemiologic and clinical research has provided a large body of evidence supporting the
developmental origins of health and disease (DOHaD), but there has been a relative dearth …

Untreated depression during pregnancy: Short-and long-term effects in offspring. A systematic review

S Gentile - Neuroscience, 2017 - Elsevier
Aim of this systematic review is to assess short-and long-lasting effects of antenatal
exposure to untreated maternal depressive symptoms. Pertinent articles were identified …