DAMPs from cell death to new life

E Vénéreau, C Ceriotti, ME Bianchi - Frontiers in immunology, 2015 - frontiersin.org
Our body handles tissue damage by activating the immune system in response to
intracellular molecules released by injured tissues [damage-associated molecular patterns …

Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs

T Behl, E Sharma, A Sehgal, I Kaur, A Kumar… - Molecular Biology …, 2021 - Springer
Diabetes mellitus (DM) has become one of the major healthcare challenges worldwide in
the recent times and inflammation being one of its key pathogenic process/mechanism affect …

Emerging role of high mobility group box-1 in thrombosis-related diseases

H Wu, R Li, LG Pei, ZH Wei, LN Kang, L Wang… - Cellular Physiology and …, 2018 - karger.com
High mobility group box-1 (HMGB-1), a typical damage-associated molecular pattern protein
released from various cells, was first identified in 1973. It is usually stored in the nuclei of …

Grafting of mesenchymal stem cell-seeded small intestinal submucosa to repair the deep partial-thickness burns

X Guo, B Xia, XB Lu, ZJ Zhang, Z Li, WL Li… - Connective Tissue …, 2016 - Taylor & Francis
Purpose: Regenerative medicine provides many treatments for burn wounds, of which cell-
seeded substitutes are encouraging for large and deep burns. To assess the feasibility of …

HMGB1-modified mesenchymal stem cells attenuate radiation-induced vascular injury possibly via their high motility and facilitation of endothelial differentiation

X Tao, M Sun, M Chen, R Ying, W Su, J Zhang… - Stem cell research & …, 2019 - Springer
Background Vascular injury is one of the most common detrimental effects of cancer
radiotherapy on healthy tissues. Since the efficacy of current preventive and therapeutic …

[HTML][HTML] Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

D Xue, W Zhang, E Chen, X Gao, L Liu, C Ye, Y Tan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Fracture nonunion and delayed union continue to pose challenges for orthopedic surgeons.
In the present study, we combined HMGB1 gelatin sponges with MSC sheets to promote …

Influence of dipeptidyl peptidase-4 (DPP4) on mesenchymal stem-cell (MSC) biology: Implications for regenerative medicine–review

B Torrecillas-Baena, MÁ Gálvez-Moreno… - Stem Cell Reviews and …, 2022 - Springer
Dipeptidyl peptidase IV (DPP4) is a ubiquitous protease that can be found in membrane-
anchored or soluble form. Incretins are one of the main DPP4 substrates. These hormones …

Oxidized high mobility group B‐1 enhances metastability of colorectal cancer via modification of mesenchymal stem/stromal cells

S Kishi, R Fujiwara‐Tani, K Honoki, R Sasaki… - Cancer …, 2022 - Wiley Online Library
High mobility group box‐1 (HMGB1) is known to be a chemotactic factor for mesenchymal
stem/stromal cells (MSCs), but the effect of post‐translational modification on its function is …

[HTML][HTML] Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers

S Ananthula, A Sinha, M El Gassim, S Batth… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resident mesenchymal stem cells (MSCs) promote cancer progression. However, pathways
and mechanisms involved in recruiting MSCs into breast tumors remain largely undefined …

Should hypoxia preconditioning become the standardized procedure for bone marrow MSCs preparation for clinical use?

YC Huang, O Parolini, L Deng, BS Yu - Stem Cells, 2016 - academic.oup.com
In recent years, mesenchymal stem/stromal cells (MSCs), especially those isolated from
bone marrow (BM-MSCs), have been utilized to treat a diverse range of diseases [1]. Many …