TLR2 and TLR4 in Parkinson's disease pathogenesis: The environment takes a toll on the gut
Parkinson's disease (PD) is an incurable, devastating disorder that is characterized by
pathological protein aggregation and neurodegeneration in the substantia nigra. In recent …
pathological protein aggregation and neurodegeneration in the substantia nigra. In recent …
Parkinson's disease and gut microbiota: from clinical to mechanistic and therapeutic studies
X Zhang, B Tang, J Guo - Translational Neurodegeneration, 2023 - Springer
Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases. The
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …
Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
Background Intraneuronal α-synuclein (α-Syn) aggregates known as Lewy bodies (LBs) and
the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the …
the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the …
Peripheral and central compensatory mechanisms for impaired vagus nerve function during peripheral immune activation
A Kobrzycka, P Napora, BL Pearson… - Journal of …, 2019 - Springer
Background Determining the etiology and possible treatment strategies for numerous
diseases requires a comprehensive understanding of compensatory mechanisms in …
diseases requires a comprehensive understanding of compensatory mechanisms in …
[PDF][PDF] and Parkinson's Disease
T Brudeka - researchgate.net
The etiology of Parkinson's disease (PD) is multifactorial, with genetics, aging, and
environmental agents all a part of the PD pathogenesis. Widespread aggregation of the α …
environmental agents all a part of the PD pathogenesis. Widespread aggregation of the α …