Elucidating the brain regions and networks associated with cognitive processes has been the mainstay of task-based fMRI, under the assumption that BOLD signals are …
J Poublanc, AP Crawley, O Sobczyk… - Journal of Cerebral …, 2015 - journals.sagepub.com
We define cerebral vascular reactivity (CVR) as the ratio of the change in blood oxygen level- dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood …
Cerebrovascular reactivity (CVR), defined as the cerebral blood flow response to a vasoactive stimulus, is an imaging biomarker with demonstrated utility in a range of diseases …
K Kazumata, KK Tha, H Narita, I Kusumi, H Shichinohe… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The mechanisms underlying frontal lobe dysfunction in moyamoya disease (MMD) are unknown. We aimed to determine whether chronic ischemia …
Background and Purpose—Increased stroke risk correlates with hemodynamic failure, which can be assessed with (15O-) H2O positron emission tomography (PET) cerebral blood flow …
O Sobczyk, A Battisti-Charbonney… - Journal of Cerebral …, 2015 - journals.sagepub.com
Attribution of vascular pathophysiology to reductions in cerebrovascular reactivity (CVR) is confounded by subjective assessment and the normal variation between anatomic regions …
OBJECT A neuroimaging assessment tool to visualize global and regional impairments in cerebral blood flow (CBF) and cerebrovascular responsiveness in individual patients with …
D Kim, TM Hughes, ME Lipford, S Craft… - Frontiers in …, 2021 - frontiersin.org
Vascular risk factors (eg, obesity and hypertension) are associated with cerebral small vessel disease, Alzheimer's disease (AD) pathology, and dementia. Reduced perfusion may …
M Silvestrini, G Viticchi, C Altamura… - Journal of …, 2012 - content.iospress.com
Increasing evidence is emerging that vascular disease and its risk factors play a role in the development of Alzheimer's disease (AD) and affect the probability of an adverse outcome …