Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

Because of their intrinsic physiochemical and biological properties together with essential
role in living organism, copper (Cu) and Cu-based nanomaterials have garnered …

Higher eukaryotes' life is impossible without copper redox activity and, literally, every breath
we take biochemically demonstrates this. However, this dependence comes at a …

Ferredoxins are a family of iron–sulfur (Fe-S) cluster proteins that serve as essential electron
donors in numerous cellular processes that are conserved through evolution. The …

Copper, an essential micronutrient, controls multiple fundamental processes throughout all
forms of life, such as respiration, cell proliferation and neurotransmitter biosynthesis. High …

Copper, an essential trace element that exists in oxidized and reduced forms, has pivotal
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …

In the past decade, evidence for the numerous roles of copper (Cu) in mammalian
physiology has grown exponentially. The discoveries of Cu involvement in cell signaling …

Copper is an essential nutrient for maintaining enzyme activity and transcription factor
function. Excess copper results in the aggregation of lipoylated dihydrolipoamide S …

Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic
acid cycle and subsequent loss of iron-sulfur cluster proteins as a unique copper-dependent …

Background Mitochondrial dysfunction and metabolic reprogramming can lead to the
development and progression of hepatocellular carcinoma (HCC). Ferredoxin 1 (FDX1) is a …