Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission

K Humphreys, CL Shover, CM Andrews, ASB Bohnert… - The Lancet, 2022 - thelancet.com
Executive summary The Stanford–Lancet Commission on the North American Opioid Crisis
was formed in response to soaring opioid-related morbidity and mortality in the USA and …

[HTML][HTML] The role of IL-1β and TNF-α in intervertebral disc degeneration

Y Wang, M Che, J Xin, Z Zheng, J Li, S Zhang - Biomedicine & …, 2020 - Elsevier
Low back pain (LBP), a prevalent and costly disease around the world, is predominantly
caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial …

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of …

ML Ferreira, K De Luca, LM Haile… - The Lancet …, 2023 - thelancet.com
Background Low back pain is highly prevalent and the main cause of years lived with
disability (YLDs). We present the most up-to-date global, regional, and national data on …

[HTML][HTML] Global low back pain prevalence and years lived with disability from 1990 to 2017: estimates from the Global Burden of Disease Study 2017

A Wu, L March, X Zheng, J Huang, X Wang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Low back pain (LBP) is a common musculoskeletal problem globally. Updating
the prevalence and burden of LBP is important for researchers and policy makers. This …

Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration

H Xing, Z Zhang, Q Mao, C Wang, Y Zhou… - Journal of …, 2021 - Springer
Exosome therapy is a promising therapeutic approach for intervertebral disc degeneration
(IVDD) and achieves its therapeutic effects by regulating metabolic disorders, the …

Prevalence, deaths, and disability‐adjusted life years due to musculoskeletal disorders for 195 countries and territories 1990–2017

S Safiri, AA Kolahi, M Cross, C Hill… - Arthritis & …, 2021 - Wiley Online Library
Objective To report the levels and trends of prevalence, deaths, and disability‐adjusted life
years (DALYs) due to musculoskeletal disorders, categorized as low back pain, neck pain …

Low back pain, a comprehensive review: pathophysiology, diagnosis, and treatment

I Urits, A Burshtein, M Sharma, L Testa, PA Gold… - Current pain and …, 2019 - Springer
Abstract Purpose of Review Low back pain encompasses three distinct sources: axial
lumbosacral, radicular, and referred pain. Annually, the prevalence of low back pain in the …

Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview

CB Oliveira, CG Maher, RZ Pinto, AC Traeger… - European Spine …, 2018 - Springer
Objective The aim of this study was to provide an overview of the recommendations
regarding the diagnosis and treatment contained in current clinical practice guidelines for …

What low back pain is and why we need to pay attention

J Hartvigsen, MJ Hancock, A Kongsted, Q Louw… - The Lancet, 2018 - thelancet.com
Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-
income countries and all age groups from children to the elderly population. Globally, years …

[HTML][HTML] Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis

PJ Owen, CT Miller, NL Mundell… - British journal of sports …, 2020 - bjsm.bmj.com
Objective Examine the effectiveness of specific modes of exercise training in non-specific
chronic low back pain (NSCLBP). Design Network meta-analysis (NMA). Data sources …