Type 2 inflammation is characterized by overexpression and heightened activity of type 2
cytokines, mediators and cells that drive neuroimmune activation and sensitization to …

Olfactory dysfunction (OD) is one of the important and difficult-to-treat symptoms of
eosinophilic chronic rhinosinusitis (CRS), which is typically associated with type 2 …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory
disease associated with type 2 (T2) cell responses and epithelial barrier, mucociliary, and …

Chronic rhinosinusitis (CRS) is a highly prevalent disease and up to 83% of CRS patients
suffer from olfactory dysfunction (OD). Because OD is specifically seen in those CRS …

Reduced sense of smell is a common symptom in patients with chronic rhinosinusitis (CRS).
Although it is often under-diagnosed by healthcare providers, reduced sense of smell can …

Objective Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal
polyps (CRSwNP) and significantly impacts health-related quality-of-life. Dupilumab …

Objective To evaluate the association between smell loss and other aspects of disease, and
evaluate dupilumab efficacy in patients with severe chronic rhinosinusitis with nasal polyps …

Zusammenfassung Hintergrund Die chronische Rhinosinusitis mit Nasenpolypen
(CRSwNP) ist eine chronisch-entzündliche Erkrankung der oberen Atemwege mit starker …

• Results from an anonymised survey demonstrated that olfactory dysfunction was the most
impactful symptom on patients' quality of life (QoL), with 71% of patients with CRSwNP …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a prevalent condition that significantly
impacts the quality of life for many individuals, particularly through the loss of smell. This …