Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

Lifestyle and dietary environmental factors in colorectal cancer susceptibility

N Murphy, V Moreno, DJ Hughes, L Vodicka… - Molecular aspects of …, 2019 - Elsevier
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle,
as evidenced historically by migrant studies and recently by extensive epidemiologic …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

The role of gut barrier dysfunction and microbiome dysbiosis in colorectal cancer development

F Genua, V Raghunathan, M Jenab… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence indicates that breakdown of the+ protective mucosal barrier of the
gut plays a role in colorectal cancer (CRC) development. Inflammation and oxidative stress …

A systematic review of microbial markers for risk prediction of colorectal neoplasia

L Yu, G Zhao, L Wang, X Zhou, J Sun, X Li… - British journal of …, 2022 - nature.com
Background Substantial evidence indicates that dysbiosis of the gut microbial community is
associated with colorectal neoplasia. This review aims to systematically summarise the …

[HTML][HTML] The antibody/microbiota interface in health and disease

D Sterlin, J Fadlallah, E Slack, G Gorochov - Mucosal immunology, 2020 - Elsevier
The human intestine is densely colonized with commensal microbes that stimulate the
immune system. While secretory Immunoglobulin (Ig) A is known to play a crucial role in gut …

The Road to Infection: Host-Microbe Interactions Defining the Pathogenicity of Streptococcus bovis/Streptococcus equinus Complex Members

C Jans, A Boleij - Frontiers in microbiology, 2018 - frontiersin.org
The Streptococcus bovis/Streptococcus equinus complex (SBSEC) comprises several
species inhabiting the animal and human gastrointestinal tract (GIT). They match the …

Bacterial involvement in progression and metastasis of colorectal neoplasia

KD Seely, AD Morgan, LD Hagenstein, GM Florey… - Cancers, 2022 - mdpi.com
Simple Summary Increasing evidence suggests that bacterial infection not only promotes
carcinogenesis in primary colorectal cancer, but also affects metastatic progression and …

Association of pre-diagnostic antibody responses to Escherichia coli and Bacteroides fragilis toxin proteins with colorectal cancer in a European cohort

J Butt, M Jenab, J Werner, V Fedirko, E Weiderpass… - Gut …, 2021 - Taylor & Francis
Experimental evidence has implicated genotoxic Escherichia coli (E. coli) and
enterotoxigenic Bacteroides fragilis (ETBF) in the development of colorectal cancer (CRC) …

Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer

A Raza, AQ Khan, VP Inchakalody, S Mestiri… - Journal of Experimental …, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis,
prognosis and therapeutic monitoring of CRC depends largely on tissue biopsy. However …