Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines
R Fraser, A Orta-Resendiz, A Mazein… - Trends in molecular …, 2023 - cell.com
SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
Innate and adaptive immune responses in the upper respiratory tract and the infectivity of SARS-CoV-2
R Ramasamy - Viruses, 2022 - mdpi.com
Increasing evidence shows the nasal epithelium to be the initial site of SARS-CoV-2
infection, and that early and effective immune responses in the upper respiratory tract (URT) …
infection, and that early and effective immune responses in the upper respiratory tract (URT) …
Safety and efficacy of the intranasal spray SARS-CoV-2 vaccine dNS1-RBD: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
F Zhu, S Huang, X Liu, Q Chen, C Zhuang… - The Lancet …, 2023 - thelancet.com
Background The live-attenuated influenza virus vector-based intranasal SARS-CoV-2
vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing …
vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing …
The nucleocapsid protein of SARS-CoV-2, combined with ODN-39M, is a potential component for an intranasal bivalent vaccine with broader functionality
Y Lobaina, R Chen, E Suzarte, P Ai, V Huerta… - Viruses, 2024 - mdpi.com
Despite the rapid development of vaccines against COVID-19, they have important
limitations, such as safety issues, the scope of their efficacy, and the induction of mucosal …
limitations, such as safety issues, the scope of their efficacy, and the induction of mucosal …
Advanced vaccine design strategies against SARS-CoV-2 and emerging variants
Vaccination is the most cost-effective means in the fight against infectious diseases. Various
kinds of vaccines have been developed since the outbreak of COVID-19, some of which …
kinds of vaccines have been developed since the outbreak of COVID-19, some of which …
[HTML][HTML] Intranasal VLP-RBD vaccine adjuvanted with BECC470 confers immunity against Delta SARS-CoV-2 challenge in K18-hACE2-mice
KS Lee, NA Rader, OA Miller-Stump, M Cooper… - Vaccine, 2023 - Elsevier
As the COVID-19 pandemic transitions into endemicity, seasonal boosters are a plausible
reality across the globe. We hypothesize that intranasal vaccines can provide better …
reality across the globe. We hypothesize that intranasal vaccines can provide better …
Intranasal HD-Ad-FS vaccine induces systemic and airway mucosal immunities against SARS-CoV-2 and systemic immunity against SARS-CoV-2 variants in mice …
The outbreak of coronavirus disease 19 (COVID-19) has highlighted the demand for
vaccines that are safe and effective in inducing systemic and airway mucosal immunity …
vaccines that are safe and effective in inducing systemic and airway mucosal immunity …
A chimeric adenovirus‐vectored vaccine based on Beta spike and Delta RBD confers a broad‐spectrum neutralization against Omicron‐included SARS‐CoV‐2 …
W Hong, H Lei, D Peng, Y Huang, C He, J Yang… - MedComm, 2024 - Wiley Online Library
Urgent research into innovative severe acute respiratory coronavirus‐2 (SARS‐CoV‐2)
vaccines that may successfully prevent various emerging emerged variants, particularly the …
vaccines that may successfully prevent various emerging emerged variants, particularly the …
A Chymotrypsin-Dependent Live-Attenuated Influenza Vaccine Provides Protective Immunity against Homologous and Heterologous Viruses
P He, M Gui, T Chen, Y Zeng, C Chen, Z Lu, N Xia… - Vaccines, 2024 - mdpi.com
Influenza virus is one of the main pathogens causing respiratory diseases in humans.
Vaccines are the most effective ways to prevent viral diseases. However, the limited …
Vaccines are the most effective ways to prevent viral diseases. However, the limited …