Recent innovations in immobilization of β-galactosidases for industrial and therapeutic applications

F Duan, T Sun, J Zhang, K Wang, Y Wen, L Lu - Biotechnology Advances, 2022 - Elsevier
Immobilized enzymes are better suited for industrial applications than free enzymes due to
their favorable properties such as ease of separation and reuse, and enhanced stability and …

Multifunctional rolling circle transcription-based nanomaterials for advanced drug delivery

X Ma, Y Zhang, K Huang, L Zhu, W Xu - Biomaterials, 2023 - Elsevier
As the up-and-comer in the development of RNA nanotechnology, RNA nanomaterials
based on functionalized rolling circle transcription (RCT) have become promising carriers for …

Single-atom platinum nanocatalyst-improved catalytic efficiency with enzyme-DNA supermolecular architectures

R Zeng, W Wang, G Cai, Z Huang, J Tao, D Tang… - Nano Energy, 2020 - Elsevier
Abstract Single-atom catalysts (SACs), a newcomer in the field of nanocatalysis, have
sparked tremendous interest thanks to their high atomic utilization, unsaturated coordination …

Horseradish peroxidase-encapsulated DNA nanoflowers: an innovative signal-generation tag for colorimetric biosensor

R Zeng, J Wang, Q Wang, D Tang, Y Lin - Talanta, 2021 - Elsevier
Herein a versatile colorimetric biosensing platform was designed for sensitive, specific, and
rapid screening of cancer-derived exosomes (HepG2 cell-derived) by introducing …

Hierarchical self-uncloaking CRISPR-Cas13a–customized RNA nanococoons for spatial-controlled genome editing and precise cancer therapy

N Fan, X Bian, M Li, J Chen, H Wu, Q Peng, H Bai… - Science …, 2022 - science.org
CRISPR-Cas13a holds enormous potential for developing precise RNA editing. However,
spatial manipulation of CRISPR-Cas13a activity remains a daunting challenge for …

Recent advances in nano-engineered approaches used for enzyme immobilization with enhanced activity

J Meena, A Gupta, R Ahuja, M Singh… - Journal of Molecular …, 2021 - Elsevier
Enzyme immobilization has been achieved on various functional nanostructures to increase
their shelf-life, enhancement of productivity, stability, reusability and develop a biocatalyst or …

Advanced Nanomaterials for Preparedness Against (Re‐) Emerging Viral Diseases

E Kim, EK Lim, G Park, C Park, JW Lim… - Advanced …, 2021 - Wiley Online Library
While the coronavirus disease (COVID‐19) accounts for the current global pandemic, the
emergence of other unknown pathogens, named “Disease X,” remains a serious concern in …

Aptamer-functionalized binary-drug delivery system for synergetic obesity therapy

X Chen, X He, R Gao, X Lan, L Zhu, K Chen, Y Hu… - ACS …, 2021 - ACS Publications
The targeted delivery of phytochemicals that promote energy expenditure for obesity therapy
remains a challenge. This study assembled a functionalized adipo-8 aptamer loaded with …

Crystallinity-tuned ultrasoft polymeric DNA networks for controlled release of anticancer drugs

K Nam, YM Kim, I Choi, HS Han, T Kim, KY Choi… - Journal of Controlled …, 2023 - Elsevier
Despite the vast interest in utilizing rolling circle amplification (RCA)-based DNA networks
for bioapplications, precise control of the mechanical and physicochemical properties is …

Aptamer functionalized nucleic acid nano drug for targeted synergistic therapy for colon cancer

L Zhu, J Yuhan, H Yu, B Zhang, L Zhu, X He… - Journal of …, 2023 - Springer
Due to its complicated pathophysiology, propensity for metastasis, and poor prognosis,
colon cancer is challenging to treat and must be managed with a combination of therapy …