Understanding Pseudomonas aeruginosa–Host Interactions: The Ongoing Quest for an Efficacious Vaccine

M Sainz-Mejías, I Jurado-Martín, S McClean - Cells, 2020 - mdpi.com
Pseudomonas aeruginosa is a leading cause of chronic respiratory infections in people with
cystic fibrosis (CF), bronchiectasis or chronic obstructive pulmonary disease (COPD), and …

Progress Toward the Elusive Pseudomonas aeruginosa Vaccine

C Merakou, MM Schaefers, GP Priebe - Surgical infections, 2018 - liebertpub.com
Background: The gram-negative bacterial pathogen Pseudomonas aeruginosa causes a
wide range of infections, mostly in hospitalized and immunocompromised patients, those …

Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa

N Hegerle, M Choi, J Sinclair, MN Amin… - PLoS …, 2018 - journals.plos.org
Klebsiella pneumoniae (KP) and Pseudomonas aeruginosa (PA) are important human
pathogens that are associated with a range of infection types, including wound and …

Immunostimulatory chimeric protein encapsulated in gelatin nanoparticles elicits protective immunity against Pseudomonas aeruginosa respiratory tract infection

M Parvaei, M Habibi, S Shahbazi, M Babaluei… - International Journal of …, 2024 - Elsevier
This study presents the design and fabrication of an innovative vaccine candidate targeting
Pseudomonas aeruginosa (P. aeruginosa). The vaccine consists of gelatin nanoparticles …

[HTML][HTML] The frequency of exotoxin A and exoenzymes S and U genes among clinical isolates of Pseudomonas aeruginosa in Shiraz, Iran

A Yousefi-Avarvand, R Khashei… - … journal of molecular …, 2015 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa as an opportunistic pathogen produces several virulence factors.
The most important of these factors are exotoxin A and type III secretion system (T3SS). The …

[HTML][HTML] Correlation of occurrence of infection in burn patients

NA Latifi, H Karimi - Annals of burns and fire disasters, 2017 - ncbi.nlm.nih.gov
The study of burn flora is helpful in determining current antibiotic susceptibilities and locating
development of multidrug resistant bacterial strains among the unit's usual flora. In this …

Exotoxin A-PLGA nanoconjugate vaccine against Pseudomonas aeruginosa infection: protectivity in murine model

L Safari Zanjani, R Shapouri, M Dezfulian… - World Journal of …, 2019 - Springer
Pseudomonas aeruginosa is the major infectious agent of concern for cystic fibrosis (CF)
patients. Therefore, it is necessary to develop appropriate strategies for preventing …

[PDF][PDF] Antibiotic resistance and frequency of class 1 integrons among Pseudomonas aeruginosa isolates obtained from wastewaters of a burn center in Northern Iran

M Ebrahimpour, I Nikokar, Y Ghasemi… - Ann Ig, 2018 - researchgate.net
Background. Pseudomonas aeruginosa, being responsible of a broad variety of infections, is
considered an important nosocomial pathogen. The emergence of multiple-drug resistance …

Immunological evaluation of an alginate‐based conjugate as a vaccine candidate against Pseudomonas aeruginosa

A Farjah, P Owlia, SD Siadat, SF Mousavi… - Apmis, 2015 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen that causes serious infections, is
usually resistant to antimicrobial agents, and is the leading cause of morbidity and …

Cloning, expression and purification of autolysin from methicillin-resistant Staphylococcus aureus: potency and challenge study in Balb/c mice

S Haghighat, SD Siadat, SMR Sorkhabadi… - Molecular …, 2017 - Elsevier
Staphylococcus aureus (MRSA) is an opportunistic pathogen which causes a variety of
clinical diseases and leads to high rates of morbidity and mortality. Development of an …