Recent developments in catalytic asymmetric aldol reactions have been summarized.
Enantioselective aldol reactions are important methods to synthesize β-hydroxy carbonyl …

This review highlights a number of additives that can be used to make asymmetric reactions
perfect. Without changing other reaction conditions, simply adding additives can lead to …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

In the area of asymmetric organocatalysis, significant effort has been dedicated during the
last decade to improve the performance of emblematic catalysts such as proline, as well as …

In recent years, enantioselective cooperative catalytic reactions, wherein two catalysts work
simultaneously to form products which cannot be obtained by the use of a single catalyst …

Strategic global industries, such as pharmaceutics, cosmetics, or crop production, are
increasingly demanding high-value enantioenriched compounds. Thus, the design and …

Enantioselectivity values represent relative rate measurements that are sensitive to the
structural features of the substrates and catalysts interacting to produce them. Therefore …

An efficient synthesis of spiropyrazolones based on organocatalysis is described. The
reaction between pyrazolones, enolizable aldehydes and enals is catalyzed by secondary …

For the first time, a highly efficient and stereoselective asymmetric aldol reaction employing
(S)-proline in the presence of solvate ionic liquids is reported. The reaction seems to …

The enantioselective tandem Michael addition–cyclization reaction between 3-methyl-2-
pyrazolin-5-one and benzylidenemalononitriles was studied with modularly designed …