Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity

R Alonso-Roman, A Last, MH Mirhakkak… - Nature …, 2022 - nature.com
Intestinal microbiota dysbiosis can initiate overgrowth of commensal Candida species–a
major predisposing factor for disseminated candidiasis. Commensal bacteria such as …

Stilbenoids as promising natural product-based solutions in a race against mycotoxigenic fungi: a comprehensive review

TM Tran, V Atanasova, C Tardif… - Journal of Agricultural …, 2023 - ACS Publications
Exposure to mycotoxins can pose a variety of adverse health effects to mammals. Despite
dozens of mycotoxin decontamination strategies applied from pre-to postharvest stages, it is …

Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence

Z Liu, P Basso, S Hossain, SD Liston… - Nature …, 2023 - nature.com
Metabolic flexibility enables fungi to invade challenging host environments. In Candida
albicans, a common cause of life-threatening infections in humans, an important contributor …

Mechanistic Insights into Toxicity of Titanium Dioxide Nanoparticles at the Micro-and Macro-levels

S Chatterjee, PC Sil - Chemical Research in Toxicology, 2024 - ACS Publications
Titanium oxide nanoparticles (TiO2 NPs) have been regarded as a legacy nanomaterial due
to their widespread usage across multiple fields. The TiO2 NPs have been and are still …

Cryptococcus neoformans Mar1 function links mitochondrial metabolism, oxidative stress, and antifungal tolerance

CL Telzrow, S Esher Righi, JM Cathey… - Frontiers in …, 2023 - frontiersin.org
Introduction: Microbial pathogens undergo significant physiological changes during
interactions with the infected host, including alterations in metabolism and cell architecture …

Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance

C Probst, S Garcia-Santamarina, JT Brooks… - PLoS …, 2022 - journals.plos.org
Copper homeostasis mechanisms are essential for microbial adaption to changing copper
levels within the host during infection. In the opportunistic fungal pathogen Cryptococcus …

[HTML][HTML] Alternative Oxidase–Aid or obstacle to combat the rise of fungal pathogens?

ESM Edrich, L Duvenage, CW Gourlay - Biochimica et Biophysica Acta …, 2024 - Elsevier
Fungal pathogens present a growing threat to both humans and global health security alike.
Increasing evidence of antifungal resistance in fungal populations that infect both humans …

Fusarium graminearum Ste3 G-Protein Coupled Receptor: A Mediator of Hyphal Chemotropism and Pathogenesis

T Sharma, PS Sridhar, C Blackman, SJ Foote… - Msphere, 2022 - Am Soc Microbiol
Fungal hyphal chemotropism has been shown to be a major contributor to host-pathogen
interactions. Previous studies on Fusarium species have highlighted the involvement of the …

Organic acids and glucose prime late-stage fungal biotrophy in maize

M Kretschmer, D Damoo, S Sun, CWJ Lee, D Croll… - Science, 2022 - science.org
Many plant-associated fungi are obligate biotrophs that depend on living hosts to proliferate.
However, little is known about the molecular basis of the biotrophic lifestyle, despite the …

With age comes resilience: how mitochondrial modulation drives age-associated fluconazole tolerance in Cryptococcus neoformans

K Yoo, S Bhattacharya, NK Oliveira, N Pereira de Sa… - mBio, 2024 - journals.asm.org
Cryptococcus neoformans (Cn) is an opportunistic fungal microorganism that causes life-
threatening meningoencephalitis. During the infection, the microbial population is …