Clathrin-mediated endocytosis (CME) is the major endocytic pathway in mammalian cells. It
is responsible for the uptake of transmembrane receptors and transporters, for remodeling …

Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

Rationale: Lipid overload-induced heart dysfunction is characterized by cardiomyocyte
death, myocardial remodeling, and compromised contractility, but the impact of excessive …

The plasma membrane is the interface between cells and their harsh environment. Uptake of
nutrients and all communication among cells and between cells and their environment …

Mutations in the human dynamin-related protein Drp1 cause mitochondria to form
perinuclear clusters. We show here that these mitochondrial clusters consist of highly …

In healthy cells, fusion and fission events participate in regulating mitochondrial morphology.
Disintegration of the mitochondrial reticulum into multiple punctiform organelles during …

Dynamins are large GTPases that belong to a protein superfamily that, in eukaryotic cells,
includes classical dynamins, dynamin-like proteins, OPA1, Mx proteins, mitofusins and …

Sequences and available structures were compared for all the widely distributed
representatives of the P-loop GTPases and GTPase-related proteins with the aim of …

Novel nanomaterials for bioassay applications represent a rapidly progressing field of
nanotechnology and nanobiotechnology. Here, we present an exploration of single-walled …

Immune interferon gamma (IFN-γ) is essential for mammalian host defense against
intracellular pathogens. IFN-γ induces nearly 2000 host genes, yet few have any assigned …