Progress in the Chemistry of Tetrahydroquinolines

I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Transition-Metal-Catalyzed Nucleophilic Dearomatization of Electron-Deficient Heteroarenes

J Jia, F Hu, Y Xia - Synthesis, 2022 - thieme-connect.com
In recent decades, transition-metal-catalyzed nucleophilic dearomatization of electron-
deficient heteroarenes, such as pyridines, quinolines, isoquinolines and nitroindoles, has …

Enantioselective Copper‐Catalyzed Quinoline Alkynylation

M Pappoppula, FSP Cardoso, BO Garrett… - Angewandte …, 2015 - Wiley Online Library
A highly enantioselective copper‐catalyzed alkynylation of quinolinium salts is reported. The
reaction employs StackPhos, a newly developed imidazole‐based chiral biaryl P, N ligand …

Enantioselective Rhodium‐Catalyzed Dearomative Arylation or Alkenylation of Quinolinium Salts

Y Wang, Y Liu, D Zhang, H Wei, M Shi… - Angewandte Chemie …, 2016 - Wiley Online Library
A highly enantioselective rhodium (I)‐catalyzed dearomative arylation or alkenylation of
easily available N‐alkylquinolinium salts is reported, thus providing an effective and …

The Hancock Alkaloids (−)-Cuspareine, (−)-Galipinine, (−)-Galipeine, and (−)-Angustureine: Asymmetric Syntheses and Corrected 1H and 13C NMR Data

SG Davies, AM Fletcher, ITT Houlsby… - Journal of natural …, 2018 - ACS Publications
The asymmetric syntheses of all members of the Hancock alkaloid family based upon a 2-
substituted N-methyl-1, 2, 3, 4-tetrahydroquinoline core are delineated. The conjugate …

The Hancock Alkaloids Angustureine, Cuspareine, Galipinine, and Galipeine: A Review of their Isolation, Synthesis, and Spectroscopic Data

SG Davies, AM Fletcher, PM Roberts… - European Journal of …, 2019 - Wiley Online Library
A review of the isolation, reported methods for the synthesis (up to the end of 2018), and
spectroscopic data of angustureine, cuspareine, galipinine, and galipeine, members of the …

Organocatalytic Approaches Towards the Synthesis of Asymmetric Tetrahydroquinoline (THQ) Derivatives

K Kant, P Naik, CK Patel, S Some, S Banerjee… - …, 2025 - thieme-connect.com
1, 2, 3, 4-Tetrahydroquinolines (THQs) are present in molecules with significant biological
importance and pharmaceuticals with diverse biological activities. Various synthetic routes …

Structural revision of the hancock alkaloid (−)-galipeine

SG Davies, AM Fletcher, ITT Houlsby… - The Journal of …, 2017 - ACS Publications
The 1H and 13C NMR data of synthetic samples of (S)-N (1)-methyl-2-[2′-(3 ″-hydroxy-4
″-methoxyphenyl) ethyl]-1, 2, 3, 4-tetrahydroquinoline, the originally proposed structure of …

A concise and efficient synthesis of tetrahydroquinoline alkaloids using the phase transfer mediated Wittig olefination reaction

G Diaz-Muñoz, RG Isidorio, IL Miranda… - Tetrahedron …, 2017 - Elsevier
The present study describes the total synthesis of 1, 2, 3, 4-tetrahydroquinoline alkaloids (±)-
galipinine,(±)-cuspareine,(±)-galipeine and (±)-angustureine, in three steps and high yields …

Total synthesis of haliclamide

S Gahalawat, SK Pandey - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
A stereoselective approach for the synthesis of haliclamide 1, a marine natural product, has
been developed. The notable features of our synthesis include MacMillan cross aldol …