Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction
caused by a dysregulated or over-reactive host response to infection. During sepsis, the …

Severe sepsis is almost invariably associated with systemic activation of coagulation. There
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Background There have been conflicting reports on the efficacy of recombinant human
activated protein C, or drotrecogin alfa (activated)(DrotAA), for the treatment of patients with …

Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome
characterized by widespread activation of coagulation leading to fibrin deposition in the …

In the majority of patients with systemic inflammatory conditions, some degree of activation
of coagulation is present. Increasing evidence points to an extensive cross‐talk between …

Disseminated intravascular coagulation (DIC) is a syndrome characterized by the systemic
activation of blood coagulation, which generates intravascular fibrin, leading to thrombosis …

The diagnosis of disseminated intravascular coagulation (DIC) should encompass both
clinical and laboratory information. The International Society for Thrombosis and …

A quick literature search in the MEDLINE databases from 1966 to 1998 using the search
term disseminated intravascular coagulation (DIC) and related key words yields an …