Neural mechanisms of movement planning: motor cortex and beyond
Highlights•Preparatory activity is a neural correlate of motor planning.•Multiple brain areas
cooperate to maintain preparatory activity.•Preparatory activity sets network activity to an …
cooperate to maintain preparatory activity.•Preparatory activity sets network activity to an …
Corticostriatal connectivity and its role in disease
GMG Shepherd - Nature Reviews Neuroscience, 2013 - nature.com
Corticostriatal projections are essential components of forebrain circuits and are widely
involved in motivated behaviour. These axonal projections are formed by two distinct …
involved in motivated behaviour. These axonal projections are formed by two distinct …
[HTML][HTML] Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain
Neuronal cell types are the nodes of neural circuits that determine the flow of information
within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides …
within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides …
Distinct descending motor cortex pathways and their roles in movement
Activity in the motor cortex predicts movements, seconds before they are initiated. This
preparatory activity has been observed across cortical layers, including in descending …
preparatory activity has been observed across cortical layers, including in descending …
A motor cortex circuit for motor planning and movement
Activity in motor cortex predicts specific movements seconds before they occur, but how this
preparatory activity relates to upcoming movements is obscure. We dissected the conversion …
preparatory activity relates to upcoming movements is obscure. We dissected the conversion …
A platform for brain-wide imaging and reconstruction of individual neurons
The structure of axonal arbors controls how signals from individual neurons are routed
within the mammalian brain. However, the arbors of very few long-range projection neurons …
within the mammalian brain. However, the arbors of very few long-range projection neurons …
Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
M Leibinger, C Zeitler, P Gobrecht… - Nature …, 2021 - nature.com
Spinal cord injury (SCI) often causes severe and permanent disabilities due to the
regenerative failure of severed axons. Here we report significant locomotor recovery of both …
regenerative failure of severed axons. Here we report significant locomotor recovery of both …
Procedures for behavioral experiments in head-fixed mice
The mouse is an increasingly prominent model for the analysis of mammalian neuronal
circuits. Neural circuits ultimately have to be probed during behaviors that engage the …
circuits. Neural circuits ultimately have to be probed during behaviors that engage the …
Functional significance of the cortico–subthalamo–pallidal 'hyperdirect'pathway
A Nambu, H Tokuno, M Takada - Neuroscience research, 2002 - Elsevier
How the motor-related cortical areas modulate the activity of the output nuclei of the basal
ganglia is an important issue for understanding the mechanisms of motor control by the …
ganglia is an important issue for understanding the mechanisms of motor control by the …
Functional anatomy of thalamus and basal ganglia
MT Herrero, C Barcia, J Navarro - Child's Nervous System, 2002 - Springer
Thalamus. The human thalamus is a nuclear complex located in the diencephalon and
comprising of four parts (the hypothalamus, the epythalamus, the ventral thalamus, and the …
comprising of four parts (the hypothalamus, the epythalamus, the ventral thalamus, and the …