Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …

Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …

Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …

Ion, particle, and fluid transport in nanofluidic devices has received considerable attention
over the past two decades due to unique transport properties exhibited at the nanoscale. 1 …

The primary structure of a protein consists of a sequence of amino acids and is a key factor
in determining how a protein folds and functions. However, conventional methods for …

We demonstrate the automated and reproducible fabrication of sub‐2‐nm nanopores in 10‐
nm thick silicon nitride membranes, through controlled dielectric breakdown in solution. Our …

In recent years, nanopores have emerged as exceptionally promising single-molecule
sensors due to their ability to detect biomolecules at subfemtomole levels in a label-free …

We report graphene nanopores with integrated optical antennae. We demonstrate that a
nanometer-sized heated spot created by photon-to-heat conversion of a gold nanorod …

The analysis of individual biological nanoparticles has significantly advanced our
understanding of fundamental biological processes but is also rapidly becoming relevant for …

DNA methylation is an epigenetic modification of DNA in which methyl groups are added at
the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated …