Carboxylic ester hydrolases in bacteria: Active site, structure, function and application
C Oh, TD Kim, KK Kim - Crystals, 2019 - mdpi.com
Carboxylic ester hydrolases (CEHs), which catalyze the hydrolysis of carboxylic esters to
produce alcohol and acid, are identified in three domains of life. In the Protein Data Bank …
produce alcohol and acid, are identified in three domains of life. In the Protein Data Bank …
Identification of protein drug targets of biofilm formation and quorum sensing in multidrug resistant Enterococcus faecalis
Enterococcus faecalis (E. faecalis) is an opportunistic multidrug-resistant (MDR) pathogen
found in the guts of humans and farmed animals. Due to the occurrence of (MDR) strain …
found in the guts of humans and farmed animals. Due to the occurrence of (MDR) strain …
Identification of potential inhibitors of sortase A: Binding studies, in-silico docking and protein-protein interaction studies of sortase A from Enterococcus faecalis
Enterococcus faecalis (Ef) is a Gram positive multidrug resistant (MDR) bacterium
contributing about 70% of total enterococcal infections. In Ef, a membrane anchored …
contributing about 70% of total enterococcal infections. In Ef, a membrane anchored …
Structural and functional characterization of peptidyl-tRNA hydrolase from Klebsiella pneumoniae
Klebsiella pneumoniae is a member of the ESKAPE panel of pathogens that are top priority
to tackle AMR. Bacterial peptidyl tRNA hydrolase (Pth), an essential, ubiquitous enzyme …
to tackle AMR. Bacterial peptidyl tRNA hydrolase (Pth), an essential, ubiquitous enzyme …
[PDF][PDF] Crystal Structure of Peptidyl-tRNA Hydrolase from Acinetobacter baumannii at 1.00 Å Resolution
The essential process of protein biosynthesis in the cell often gets stalled due to the
premature abortion of the translation process and generates a byproduct of peptidyl-tRNA …
premature abortion of the translation process and generates a byproduct of peptidyl-tRNA …
Multiple target sites for designing candidate drugs
DM Salunke - Biochemical Journal, 2018 - portlandpress.com
Rational drug discovery strategy requires a design of small molecules as candidate drugs
which can specifically inhibit a target protein or any other macromolecule and effectively …
which can specifically inhibit a target protein or any other macromolecule and effectively …