Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

Implantation failure in assisted reproduction is thought to be mainly due to impaired uterine
receptivity. With normal uterine anatomy, changes in endocrine profile during ovarian …

Menstruation drives cyclic activation of endometrial progenitor cells, tissue regeneration,
and maturation of stromal cells, which differentiate into specialized decidual cells prior to …

Recurrent pregnancy loss (RPL), defined as multiple consecutive miscarriages, is a
devastating disorder for which there are no good treatment options. Two opposing …

Implantation requires highly orchestrated interactions between the developing embryo and
maternal endometrium. The association between abnormal implantation and reproductive …

Decidualization is characterized by a series of genetic, metabolic, morphological,
biochemical, vascular and immune changes occurring in the endometrial stroma in …

Despite advances in assisted reproductive techniques in the 4 decades since the first
human birth after in vitro fertilisation, 1–2% of couples experience recurrent implantation …

Humans are shaped by evolution through natural selection, as are all species. While
evolution is central to all biological processes, the key stage for competition and selection is …

Follicle-stimulating hormone (FSH) promotes the production and secretion of estrogen,
which in turn stimulates the growth and maturation of ovarian follicles. Therefore …

STUDY QUESTION Is implantation failure following ART associated with a perturbed
decidual response in endometrial stromal cells (EnSCs)? SUMMARY ANSWER Dynamic …