The development of reliable water oxidation catalysts (WOCs) is essential for implementing
artificial photosynthesis on a large technological scale. WOC research has evolved into two …

Highlights•Time-resolved serial femtosecond crystallography (tr-SFX) probes structure and
function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …

In this review, we describe recent research developments into radiation damage effects in
macromolecular X-ray crystallography observed at synchrotrons and X-ray free electron …

X-ray crystallography enables detailed structural studies of proteins to understand and
modulate their function. Conducting crystallographic experiments at cryogenic temperatures …

Radiation damage remains one of the major bottlenecks to accurate structure solution in
protein crystallography. It can induce structural and chemical changes in protein crystals …

X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights
into structural dynamics of biological macromolecule solutions. However, very high dose …

With recent developments in X-ray sources, instrumentation and data-analysis tools, time-
resolved crystallographic experiments, which were originally the preserve of a few expert …

Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility
to routinely collect data at room temperature using micrometre-sized crystals of biological …

Soluble methane monooxygenase (sMMO) is a multicomponent metalloenzyme that
catalyzes the conversion of methane to methanol at ambient temperature using a nonheme …

The recently discovered lytic polysaccharide monooxygenases (LPMOs) are Cu-containing
enzymes capable of degrading polysaccharide substrates oxidatively. The generally …