Natural alkylated hydroxy cinnamates (AHCs) isolated from medicinal plants and the thereby
designed and synthesized cinnamides are derivatives of hydroxy cinnamic acids such as p …

Betulinic acid (BA, 3β-hydroxy-lup-20 (29)-en-28-oic acid) is a pentacyclic triterpene acid
present predominantly in Betula ssp.(Betulaceae) and is also widely spread in many species …

The apicoplast is an essential organelle for the viability of apicomplexan parasites
Plasmodium falciparum or Toxoplasma gondii, which has been proposed as a suitable drug …

Abstract p-Coumaric acid is a known inhibitor of tyrosinase, an enzyme involved in the initial
steps of the melanin synthesis in human and other species. However, its low lipophilicity …

A series of monocationic new guanidinobenzimidazole derivatives were prepared in a four
step process starting from 2-nitro-1, 4-phenylendiamine. Their antiparasitic activity against …

In low-income populations, neglected diseases are the principal cause of mortality. Of these,
leishmaniasis and malaria, being parasitic, protozoan infections, affect millions of people …

A series of synthetic N‐acylpyrrolidone and‐piperidone derivatives of the natural alkaloid
piperlongumine were prepared and tested for their activities against Leishmania major and …

Twelve new pyridine-4 (1 H)-one derivatives, namely, 8-demethoxywaltherione F (1),
waltheriones R–V (2, 6, 7, 10, and 11), 1-methoxywaltherione O (3),(S)-15 …

Chagas disease, or American trypanosomiasis, is a neglected tropical disease which is a
top priority target of the World Health Organization. The disease, endemic mainly in Latin …

Species of the genus Pleiocarpa are used in traditional medicine against fever and malaria.
The present study focuses on the isolation and identification of bioactive compounds from P …