Based on recent research, the non-coding genome is essential for controlling genes and
genetic programming during development, as well as for health and cardiovascular …

Cardiac fibrosis is a significant driver of congestive heart failure, a syndrome that continues
to affect a growing patient population globally. Cardiac fibrosis results from a constellation of …

Skeletal muscle regeneration relies on the reciprocal interaction between many types of
cells. Regenerative capacity may be altered in different disorders. In our study, we …

MicroRNAs (miRNAs) control the expression of diverse subsets of target mRNAs, and
studies have found miRNA dysregulation in failing hearts. Expression of miR-29 is abundant …

Chronic kidney disease (CKD) is an independent risk factor for the development of heart
failure, but the underlying mechanisms remain unknown. Using a novel translational swine …

Members of the microRNA-29 (miR-29) gene family have been implicated as suppressors of
collagen in several human diseases. The present study aimed to explore the function of miR …

Non-cardiomyocytes (nonCMs) play an important part in cardiac fibrosis pathophysiology,
but the underlying molecular pathways are unknown. Semaglutide has cardioprotective …

T. forsythia is a subgingival periodontal bacterium constituting the subgingival pathogenic
polymicrobial milieu during periodontitis (PD). miRNAs play a pivotal role in maintaining …

Aging is a consequence of complex molecular changes, but whether a single microRNA
(miRNA) can drive aging remains unclear. A miRNA known to be upregulated during both …

MicroRNAs (miRNAs) play important roles in the regulation of cellular function and fate via
post-transcriptional regulation of gene expression. Although several miRNAs are associated …