Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Antibiotics and antibiotic resistance from animal manures to soil: a review

WY Xie, Q Shen, FJ Zhao - European journal of soil science, 2018 - Wiley Online Library
The overuse of veterinary antibiotics in animal production and the subsequent land
applications of manures contribute to the elevated antibiotic resistance in the soil …

Manure as a potential hotspot for antibiotic resistance dissemination by horizontal gene transfer events

T Lima, S Domingues, GJ Da Silva - Veterinary sciences, 2020 - mdpi.com
The increasing demand for animal-derived foods has led to intensive and large-scale
livestock production with the consequent formation of large amounts of manure. Livestock …

Antibiotics and antibiotic resistance genes in animal manure–consequences of its application in agriculture

M Zalewska, A Błażejewska, A Czapko… - Frontiers in …, 2021 - frontiersin.org
Antibiotic resistance genes (ARGs) are a relatively new type of pollutant. The rise in
antibiotic resistance observed recently is closely correlated with the uncontrolled and …

The rise and spread of mcr plasmid-mediated polymyxin resistance

SC Nang, J Li, T Velkov - Critical reviews in microbiology, 2019 - Taylor & Francis
Polymyxins are important lipopeptide antibiotics that serve as the last-line defense against
multidrug-resistant (MDR) Gram-negative bacterial infections. Worryingly, the clinical utility …

Occurrence and Characteristics of Mobile Colistin Resistance (mcr) Gene-Containing Isolates from the Environment: A Review

MU Anyanwu, IF Jaja, OC Nwobi - International journal of environmental …, 2020 - mdpi.com
The emergence and spread of mobile colistin (COL) resistance (mcr) genes jeopardize the
efficacy of COL, a last resort antibiotic for treating deadly infections. COL has been used in …

Occurrence of the mcr-1 Colistin Resistance Gene and other Clinically Relevant Antibiotic Resistance Genes in Microbial Populations at Different Municipal …

N Hembach, F Schmid, J Alexander, C Hiller… - Frontiers in …, 2017 - frontiersin.org
Seven wastewater treatment plants (WWTPs) with different population equivalents and
catchment areas were screened for the prevalence of the colistin resistance gene mcr-1 …

Antimicrobial resistance and food animals: Influence of livestock environment on the emergence and dissemination of antimicrobial resistance

N Vidovic, S Vidovic - Antibiotics, 2020 - mdpi.com
The emergence and dissemination of antimicrobial resistance among human, animal and
zoonotic pathogens pose an enormous threat to human health worldwide. The use of …

An update of mobile colistin resistance in non-fermentative gram-negative bacilli

P Khuntayaporn, K Thirapanmethee… - Frontiers in Cellular …, 2022 - frontiersin.org
Colistin, the last resort for multidrug and extensively drug-resistant bacterial infection
treatment, was reintroduced after being avoided in clinical settings from the 1970s to the …

First report of an Escherichia coli strain from swine carrying an OXA-181 carbapenemase and the colistin resistance determinant MCR-1

S Pulss, T Semmler, E Prenger-Berninghoff… - International journal of …, 2017 - Elsevier
Plasmid-mediated resistance to carbapenems and colistin in Enterobacteriaceae represents
an emerging public health threat. Although animals have been identified as a relevant …