[HTML][HTML] Glycosylation and behavioral symptoms in neurological disorders

P Pradeep, H Kang, B Lee - Translational Psychiatry, 2023 - nature.com
Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is
a complex post-translational modification that plays a crucial role in cellular function. It is …

Accelerating research on biological aging and mental health: Current challenges and future directions

LKM Han, JE Verhoeven, AR Tyrka… - …, 2019 - Elsevier
Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Depression: Biological markers and treatment

GN Erjavec, M Sagud, MN Perkovic, DS Strac… - Progress in Neuro …, 2021 - Elsevier
Nowadays depression is considered as a systemic illness with different biological
mechanisms involved in its etiology, including inflammatory response, hypothalamic …

Inflammatory markers in substance use and mood disorders: a neuroimaging perspective

K Agarwal, P Manza, M Chapman, N Nawal… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to addictive drugs in substance use disorders and stressors in mood
disorders render the brain more vulnerable to inflammation. Inflammation in the brain, or …

Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies

SE Williams, RG Mealer, EM Scolnick, JW Smoller… - Molecular …, 2020 - nature.com
Glycosylation, the enzymatic attachment of carbohydrates to proteins and lipids, regulates
nearly all cellular processes and is critical in the development and function of the nervous …

The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation

RG Mealer, BG Jenkins, CY Chen, MJ Daly, T Ge… - Scientific Reports, 2020 - nature.com
A common missense variant in SLC39A8 is convincingly associated with schizophrenia and
several additional phenotypes. Homozygous loss-of-function mutations in SLC39A8 result in …

MS-based glycomics: An analytical tool to assess nervous system diseases

W Peng, F Kobeissy, S Mondello, C Barsa… - Frontiers in …, 2022 - frontiersin.org
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …

Hair cortisol level might be indicative for a 3PM approach towards suicide risk assessment in depression: comparative analysis of mentally stable and depressed …

A Karabatsiakis, K de Punder, J Salinas-Manrique… - EPMA journal, 2022 - Springer
Depression and suicidal behavior are interrelated, stress-associated mental health
conditions, each lacking biological verifiability. Concepts of predictive, preventive, and …

Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants

J Sun, W Wang, R Zhang, H Duan, X Tian, C Xu… - Translational …, 2022 - nature.com
To date, little is known about the pleiotropic genetic variants among depression, cognition,
and memory. The current research aimed to identify the potential pleiotropic single …

Glycosylation changes of vWF in circulating extracellular vesicles to predict depression

N Yamada, K Tominaga, N Tominaga, A Kobayashi… - Scientific Reports, 2024 - nature.com
The clinical diagnosis of major depressive disorder (MDD) still depends on subjective
information in terms of various symptoms regarding mood. Detecting the characterization of …