Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

A Photoelectrochemical Nanoreactor for Single‐Cell Sampling and Near Zero‐Background Faradaic Detection of Intracellular microRNA

HY Wang, YT Xu, B Wang, SY Yu, XM Shi… - Angewandte …, 2022 - Wiley Online Library
Rational utilization of the rich light‐bio‐matter interplay taking place in single‐cell analysis
represents a new technological direction in the field. The light‐fueled operation is expected …

Recent advances in luminescent materials for super-resolution imaging via stimulated emission depletion nanoscopy

Y Xu, R Xu, Z Wang, Y Zhou, Q Shen, W Ji… - Chemical Society …, 2021 - pubs.rsc.org
Stimulated emission depletion (STED) nanoscopy is a promising fluorescence microscopy to
detect unresolvable structures at the nanoscale level and then achieve a superior imaging …

Recent advances in ruthenium (II) and iridium (III) complexes containing nanosystems for cancer treatment and bioimaging

J Shen, TW Rees, L Ji, H Chao - Coordination chemistry reviews, 2021 - Elsevier
Ruthenium (II) and iridium (III) coordination compounds display excellent structural,
photophysical, and biological properties which make them highly promising as anticancer …

Phosphorescent metal complexes as theranostic anticancer agents: combining imaging and therapy in a single molecule

CP Tan, YM Zhong, LN Ji, ZW Mao - Chemical Science, 2021 - pubs.rsc.org
Phosphorescent metal complexes are a new kind of multifunctional antitumor compounds
that can integrate imaging and antitumor functions in a single molecule. In this minireview …

“Dual-key-and-lock” ruthenium complex probe for lysosomal formaldehyde in cancer cells and tumors

C Liu, R Zhang, W Zhang, J Liu, YL Wang… - Journal of the …, 2019 - ACS Publications
Biomedical investigations reveal that excessive formaldehyde generation is possibly a
critical factor for tissue cancerization, cancer progression, and metastasis. Responsive …

Fluorescent probes for nanoscopic imaging of mitochondria

S Samanta, Y He, A Sharma, J Kim, W Pan, Z Yang… - Chem, 2019 - cell.com
Studying the ultra-fine structure and functions of mitochondria at a nanoscale level has
garnered tremendous attention from biologists. Mitochondria perform many more functions …

Mitochondrion-specific blinking fluorescent bioprobe for nanoscopic monitoring of mitophagy

Z Ye, L Wei, X Geng, X Wang, Z Li, L Xiao - ACS nano, 2019 - ACS Publications
Dynamic changes of mitochondrial morphology play an important role in cellular
metabolism. Real-time monitoring mitochondrial ultrastructural dynamics at nanometer-scale …

Super‐resolution tracking of mitochondrial dynamics with an Iridium (III) luminophore

Q Chen, C Jin, X Shao, R Guan, Z Tian, C Wang, F Liu… - Small, 2018 - Wiley Online Library
Combining luminescent transition metal complex with super‐resolution microscopy is an
excellent strategy for the long‐term visualization of the dynamics of subcellular structures in …