Targeting autophagy using metallic nanoparticles: A promising strategy for cancer treatment

M Cordani, Á Somoza - Cellular and molecular life sciences, 2019 - Springer
Despite the extensive genetic and phenotypic variations present in the different tumors, they
frequently share common metabolic alterations, such as autophagy. Autophagy is a self …

Experimental considerations on the cytotoxicity of nanoparticles

B Kong, JH Seog, LM Graham, SB Lee - Nanomedicine, 2011 - Taylor & Francis
Engineered nanoparticles are one of the leading nanomaterials currently under
investigation due to their applicability in various fields, including drug and gene delivery …

Toxicity of silica nanoparticles depends on size, dose, and cell type

IY Kim, E Joachim, H Choi, K Kim - … : Nanotechnology, Biology and Medicine, 2015 - Elsevier
Monodisperse spherical silica nanoparticles (SNPs) with diameters of 20–200 nm were
employed to study size, dose, and cell-type dependent cytotoxicity in A549 and HepG2 …

In vitro cytotoxicity effect and antibacterial performance of human lung epithelial cells A549 activity of zinc oxide doped TiO2 nanocrystals: investigation of bio-medical …

K Kaviyarasu, N Geetha, K Kanimozhi… - Materials Science and …, 2017 - Elsevier
We report the synthesis of high quality ZnO doped TiO 2 nanocrystals by chemical method at
room temperature (RT), it can cause serious oxidative stress and DNA damage to human …

Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic

H Zhang, DR Dunphy, X Jiang, H Meng… - Journal of the …, 2012 - ACS Publications
We have developed structure/toxicity relationships for amorphous silica nanoparticles (NPs)
synthesized through low-temperature colloidal (eg, Stöber silica) or high-temperature …

The size-dependent cytotoxicity of amorphous silica nanoparticles: a systematic review of in vitro studies

X Dong, Z Wu, X Li, L Xiao, M Yang, Y Li… - International journal …, 2020 - Taylor & Francis
With the increasing production and application of engineered amorphous silica
nanoparticles (aSiNPs), people have more opportunities to be exposed to aSiNPs. However …

Preparation of colloidal mesoporous silica nanoparticles with different diameters and their unique degradation behavior in static aqueous systems

H Yamada, C Urata, Y Aoyama, S Osada… - Chemistry of …, 2012 - ACS Publications
The degradation of colloidal mesoporous silica nanoparticles (CMPS) is quite important for
the design of stable catalyst supports and biodegradable drug delivery systems carriers. The …

A systematic study of hexavalent chromium adsorption and removal from aqueous environments using chemically functionalized amorphous and mesoporous silica …

EH Jang, SP Pack, I Kim, S Chung - Scientific reports, 2020 - nature.com
We report on the synthesis and characterization of highly monodisperse amorphous silica
nanoparticles (ASNs) and mesoporous silica nanoparticles (MSNs) with particle sizes of 15 …

Physico-chemical features of engineered nanoparticles relevant to their toxicity

B Fubini, M Ghiazza, I Fenoglio - Nanotoxicology, 2010 - Taylor & Francis
Nanotoxicology studies require investigations of several physico-chemical aspects of the
particle/body fluid interaction, here described by reviewing recent literature in the light of …

Surface functionalization of silica nanoparticles supports colloidal stability in physiological media and facilitates internalization in cells

C Graf, Q Gao, I Schütz, CN Noufele, W Ruan… - Langmuir, 2012 - ACS Publications
The influence of the surface functionalization of silica particles on their colloidal stability in
physiological media is studied and correlated with their uptake in cells. The surface of 55±2 …