2D hetero-nanoconstructs of black phosphorus for breast cancer theragnosis: technological advancements
As per global cancer statistics of 2020, female breast cancer is the most commonly
diagnosed cancer and also the foremost cause of cancer death in women. Traditional …
diagnosed cancer and also the foremost cause of cancer death in women. Traditional …
Analytical and bioanalytical HPLC method for simultaneous estimation of 5-fluorouracil and sonidegib
Aim: To develop a new sensitive RP-HPLC method for simultaneous estimation of 5-
fluorouracil (5-FU) and sonidegib (SDG). Materials & methods: Analytical and bioanalytical …
fluorouracil (5-FU) and sonidegib (SDG). Materials & methods: Analytical and bioanalytical …
Interaction of letrozole and its degradation products with aromatase: Chemometric assessment of kinetics and structure-based binding validation
Letrozole is one of the most prescribed drugs for the treatment of breast cancer in post-
menopausal women, and it is endowed with selective peripheral aromatase inhibitory …
menopausal women, and it is endowed with selective peripheral aromatase inhibitory …
[PDF][PDF] QbD-driven HPLC method for the quantification of rivastigmine in rat plasma and brain for pharmacokinetics study
The goal of the study was to develop a high throughput quantification method with precision
and accuracy in plasma and brain matrices for Rivastigmine (RST). For the method …
and accuracy in plasma and brain matrices for Rivastigmine (RST). For the method …
[HTML][HTML] Green analytical chemistry and quality by design: A combined approach towards simultaneous determination of Letrozole with its co-administered Zoledronic …
NA Abd El-Fatah, HT Elbalkiny, MA Hegazy… - … of Pharmaceutical and …, 2024 - Elsevier
Nowadays, breast cancer is the most affecting and globally diagnosed malignancy among
women, yet Letrozole (LTZ) was considered the first-line treatment as hormonal anticancer …
women, yet Letrozole (LTZ) was considered the first-line treatment as hormonal anticancer …
A DoE-based fast and synchronous quantification of rhein, aceclofenac, and diclofenac by RP-HPLC-DAD method in spiked Wistar rat plasma: application to …
A fixed-dose combination of diacerein and aceclofenac (ACF) is commonly used in the
treatment of osteoarthritis for their disease-modifying and analgesic effects, respectively. We …
treatment of osteoarthritis for their disease-modifying and analgesic effects, respectively. We …
CYP19A1 mediates severe SARS-CoV-2 disease outcome in males
S Stanelle-Bertram, S Beck, NK Mounogou… - Cell Reports …, 2023 - cell.com
Male sex represents one of the major risk factors for severe COVID-19 outcome. However,
underlying mechanisms that mediate sex-dependent disease outcome are as yet unknown …
underlying mechanisms that mediate sex-dependent disease outcome are as yet unknown …
[HTML][HTML] Pharmacokinetic and Safety Evaluation of MBZM-N-IBT, A Lead Against Chikungunya Virus
AK Moharana, TK Mohapatra… - Biomedical and …, 2024 - biomedpharmajournal.org
Chikungunya virus (CHIKV) infection was previously found to be inhibited by MBZM-N-IBT
both in vitro and in vivo. To further assess its suitability for in vivo application, toxicity and …
both in vitro and in vivo. To further assess its suitability for in vivo application, toxicity and …
[HTML][HTML] Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form
Introduction: Posaconazole is a widely used antifungal drug, and its accurate quantification
is essential for quality control and assessment of its pharmaceutical products. This study …
is essential for quality control and assessment of its pharmaceutical products. This study …
Quantification of oteseconazole in rat plasma using LC-MS/MS and its application to pharmacokinetic study
KPC Susararla, O Shelke, N Shorgar - Journal of Applied …, 2024 - japtronline.com
Background: Oteseconazole is a new molecule launched for human treatment. However, the
information is not available in the public domain for analyzing blood samples. This study …
information is not available in the public domain for analyzing blood samples. This study …