Cardiac telocytes—their junctions and functional implications

M Gherghiceanu, LM Popescu - Cell and tissue research, 2012 - Springer
Telocytes (TCs) form a cardiac network of interstitial cells. Our previous studies have shown
that TCs are involved in heterocellular contacts with cardiomyocytes and cardiac …

Genetics of human and canine dilated cardiomyopathy

S Simpson, J Edwards… - … journal of genomics, 2015 - Wiley Online Library
Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated
cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third …

Outcome in phospholamban R14del carriers: results of a large multicentre cohort study

IAW van Rijsingen, PA van der Zwaag… - Circulation …, 2014 - Am Heart Assoc
Background—The pathogenic phospholamban R14del mutation causes dilated and
arrhythmogenic right ventricular cardiomyopathies and is associated with an increased risk …

New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants

C Andreasen, JB Nielsen, L Refsgaard… - European Journal of …, 2013 - nature.com
Cardiomyopathies are a heterogeneous group of diseases with various etiologies. We
focused on three genetically determined cardiomyopathies: hypertrophic (HCM), dilated …

Sudden unexpected death in epilepsy genetics: molecular diagnostics and prevention

AM Goldman, ER Behr, C Semsarian, RD Bagnall… - …, 2016 - Wiley Online Library
Epidemiologic studies clearly document the public health burden of sudden unexpected
death in epilepsy (SUDEP). Clinical and experimental studies have uncovered dynamic …

Genetic basis of dilated cardiomyopathy in dogs and its potential as a bidirectional model

KR Gaar-Humphreys, TCF Spanjersberg, G Santarelli… - Animals, 2022 - mdpi.com
Simple Summary Heart disease is a leading cause of death for both humans and dogs.
Inherited heart diseases, including dilated cardiomyopathy (DCM), account for a proportion …

Risk of cardiovascular disease in family members of young sudden cardiac death victims

MF Ranthe, BG Winkel, EW Andersen… - European heart …, 2013 - academic.oup.com
Aims Descriptive and genetic studies suggest that relatives of sudden cardiac death (SCD)
victims have an increased risk of several cardiovascular diseases (CVDs). Given the severe …

[HTML][HTML] Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation

TL Lynch IV, MA Ismahil, AG Jegga, MJ Zilliox… - Journal of molecular and …, 2017 - Elsevier
Cardiomyopathies are a leading cause of heart failure and are often caused by mutations in
sarcomeric genes, resulting in contractile dysfunction and cellular damage. This may …

Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype

K Kolokotronis, J Kühnisch, E Klopocki… - Human …, 2019 - Wiley Online Library
Dominant mutations in the MYH7 and MYBPC3 genes are common causes of inherited
cardiomyopathies, which often demonstrate variable phenotypic expression and incomplete …

Genomic insights into cardiomyopathies: A comparative cross-species review

S Simpson, P Rutland, CS Rutland - Veterinary sciences, 2017 - mdpi.com
In the global human population, the leading cause of non-communicable death is
cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular …