T cell migration is essential for T cell responses; it allows for the detection of cognate antigen
at the surface of antigen-presenting cells and for interactions with other cells involved in the …

In search of foreign antigens, lymphocytes recirculate from the blood, through lymph nodes,
into lymphatics and back to the blood. Dendritic cells also migrate to lymph nodes for optimal …

Upon infection, adaptive immune responses play catch-up with rapidly replicating
pathogens. While mechanisms for efficient humoral responses to lymph-borne antigens …

During cell migration, the movement of the nucleus must be coordinated with the
cytoskeletal dynamics at the leading edge and trailing end, and, as a result, undergoes …

To initiate adaptive immunity, dendritic cells (DCs) move from parenchymal tissues to
lymphoid organs by migrating along stromal scaffolds that display the glycoprotein …

Aging affects all tissues and organs. Aging of the immune system results in the severe
disruption of its functions, leading to an increased susceptibility to infections, an increase in …

Antigen-specific immunity requires regulated trafficking of T cells in and out of diverse
tissues in order to orchestrate lymphocyte development, immune surveillance, responses …

Chemokines are pivotal regulators of cell migration during continuous immune surveillance,
inflammation, homeostasis, and development. Chemokine binding to their 7-transmembrane …

Chemokines orchestrate immune cell trafficking by eliciting either directed or random
migration and by activating integrins in order to induce cell adhesion. Analyzing dendritic …

A prominent activity of the chemokine system is the regulation of leukocyte trafficking. Here
we summarize recent findings on the initial steps in chemokine receptor–induced signal …