[HTML][HTML] HIV-1 drug resistance mutations: an updated framework for the second decade of HAART

RW Shafer, JM Schapiro - AIDS reviews, 2008 - ncbi.nlm.nih.gov
More than 200 mutations are associated with antiretroviral resistance to drugs belonging to
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …

The HIVdb system for HIV-1 genotypic resistance interpretation

MW Tang, TF Liu, RW Shafer - Intervirology, 2012 - karger.com
Abstract The Stanford HIV Drug Resistance Database hosts a freely available online
genotypic resistance interpretation system called HIVdb to help clinicians and laboratories …

[HTML][HTML] Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other …

AC Pineda-Peña, NR Faria, S Imbrechts, P Libin… - Infection, genetics and …, 2013 - Elsevier
Background To investigate differences in pathogenesis, diagnosis and resistance pathways
between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed …

Varied patterns of HIV-1 drug resistance on failing first-line antiretroviral therapy in South Africa

CL Wallis, JW Mellors, WDF Venter… - JAIDS Journal of …, 2010 - journals.lww.com
Background: The South African national antiretroviral therapy roll-out program is entering its
sixth year, with over 570,000 adults accessing treatment. HIV-1 drug resistance is a potential …

Molecular epidemiology of HIV-1 in Eastern Europe and Russia

MAA van de Klundert, A Antonova, G Di Teodoro… - Viruses, 2022 - mdpi.com
The HIV epidemic in Eastern Europe and Russia is large and not well-controlled. To
describe the more recent molecular epidemiology of HIV-1, transmitted drug resistance, and …

Cohort profile: the Danish HIV cohort study

N Obel, FN Engsig, LD Rasmussen… - International journal …, 2009 - academic.oup.com
Shortly after AIDS was recognized in USA, the first cases were diagnosed in Denmark. 1, 2
Today Denmark has a population of 5.3 million citizens and the prevalence of HIV infection …

A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells

SA Yukl, E Sinclair, M Somsouk, PW Hunt, L Epling… - Aids, 2014 - journals.lww.com
We compared different techniques for measuring gut HIV reservoirs and assessed for HIV in
non-CD4+ T cells. HIV DNA levels were similar when measured from rectal biopsies and …

The Effect of treatment-associated mutations on HIV replication and transmission cycles

MM Johnson, CE Jones, DN Clark - Viruses, 2022 - mdpi.com
HIV/AIDS mortality has been decreasing over the last decade. While promising, this
decrease correlated directly with increased use of antiretroviral drugs. As a natural …

Acute retroviral syndrome is associated with high viral burden, CD4 depletion, and immune activation in systemic and tissue compartments

TA Crowell, DJ Colby, S Pinyakorn… - Clinical Infectious …, 2018 - academic.oup.com
Background Many individuals with acute human immunodeficiency virus infection (AHI)
experience acute retroviral syndrome (ARS), which is associated with adverse long-term …

The impact of HIV genetic polymorphisms and subtype differences on the occurrence of resistance to antiretroviral drugs

MA Wainberg, BG Brenner - Molecular biology international, 2012 - Wiley Online Library
The vast majority of reports on drug resistance deal with subtype B infections in developed
countries, and this is largely due to historical delays in access to antiretroviral therapy (ART) …