▪ Abstract Fatty acid amide hydrolase (FAAH) is a mammalian integral membrane enzyme
that degrades the fatty acid amide family of endogenous signaling lipids, which includes the …

Abstract Aminoacyl-tRNAs (aa-tRNAs) are the essential substrates for translation. Most aa-
tRNAs are formed by direct aminoacylation of tRNA catalyzed by aminoacyl-tRNA …

Fatty acid amides constitute a large and diverse class of lipid transmitters that includes the
endogenous cannabinoid anandamide and the sleep-inducing substance oleamide. The …

Abstract Amidases (EC 3. 5. 1. X) are versatile biocatalysts for synthesis of chiral carboxylic
acids, α-amino acids and amides due to their hydrolytic and acyl transfer activity towards the …

Monotopic membrane proteins, classified by topology, are proteins that embed into a single
face of the membrane. These proteins are generally underrepresented in the Protein Data …

An acrylamide biosensor was developed by utilizing purine bases, ie guanine and adenine,
through computational and electrochemical approaches. The molecular docking simulation …

The Type VI secretion system (T6SS) is a bacterial nanomachine that delivers toxic effectors
to kill competitors or subvert some of their key functions. Here, we use transposon directed …

Phenotypic screening has identified small-molecule modulators of aging, but the mechanism
of compound action often remains opaque due to the complexities of mapping protein …

The soil bacterial isolate Variovorax sp. strain SRS16 mineralizes the phenylurea herbicide
linuron. The proposed pathway initiates with hydrolysis of linuron to 3, 4-dichloroaniline …

Abstract Amidase 1 (AMI1) from Arabidopsis thaliana converts indole-3-acetamide (IAM),
into indole-3-acetic acid (IAA). AMI 1 is part of a small isogene family comprising seven …