Zebrafish as a vertebrate model system to evaluate effects of environmental toxicants on cardiac development and function

S Sarmah, JA Marrs - International journal of molecular sciences, 2016 - mdpi.com
Environmental pollution is a serious problem of the modern world that possesses a major
threat to public health. Exposure to environmental pollutants during embryonic development …

Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder

Y Fernandes, DM Buckley… - Biochemistry and Cell …, 2018 - cdnsciencepub.com
The term fetal alcohol spectrum disorder (FASD) refers to the entire suite of deleterious
outcomes resulting from embryonic exposure to alcohol. Along with other reviews in this …

AHR/cyp1b1 signaling-mediated extrinsic apoptosis contributes to 6PPDQ-induced cardiac dysfunction in zebrafish embryos

Y Jiang, M Zhang, J Li, K Hu, T Chen - Environmental Pollution, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPDQ) has
raised significant concerns due to its widespread distribution and high toxicity to aquatic …

Folic acid reduces the ethanol-induced morphological and behavioral defects in embryonic and larval zebrafish (Danio rerio) as a model for fetal alcohol spectrum …

PG Cadena, MRS Cadena, S Sarmah, JA Marrs - Reproductive Toxicology, 2020 - Elsevier
The objective of this work was to determine whether folic acid (FA) reduces the embryonic
ethanol (EtOH) exposure induced behavioral and morphological defects in our zebrafish …

Zebrafish models of fetal alcohol spectrum disorders

Y Fernandes, CB Lovely - genesis, 2021 - Wiley Online Library
Fetal alcohol spectrum disorder (FASD) describes a wide range of structural deficits and
cognitive impairments. FASD impacts up to 5% of children born in the United States each …

An Overview of Adverse Outcome Pathway Links between PM2.5 Exposure and Cardiac Developmental Toxicity

C Liang, R Ding, Q Sun, S Liu, Z Sun… - Environment & …, 2024 - ACS Publications
Fine particulate matter (PM2. 5) is a significant risk factor for birth defects. As the first and
most important organ to develop during embryogenesis, the heart's potential susceptibility to …

The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish

WA Thompson, Z Shvartsburd, MM Vijayan - Aquatic Toxicology, 2022 - Elsevier
Venlafaxine, a selective serotonin and norepinephrine reuptake inhibitor, is a highly
prescribed antidepressant and is detected at µg/L concentrations in waterways receiving …

Common congenital anomalies: Environmental causes and prevention with folic acid containing multivitamins

S Sarmah, P Muralidharan… - Birth Defects Research …, 2016 - Wiley Online Library
Congenital anomalies, congenital defects, or birth defects are significant causes of death in
infants. The most common congenital defects are congenital heart defects (CHDs) and …

Prenatal alcohol exposure induced congenital heart diseases: From bench to bedside

Z Chen, S Li, L Guo, X Peng, Y Liu - Birth Defects Research, 2021 - Wiley Online Library
Alcohol consumption is increasing worldwide. Many child‐bearing‐aged women consume
alcohol during pregnancy, intentionally or unintentionally, thereby increasing the potential …

Prenatal alcohol exposure causes adverse cardiac extracellular matrix changes and dysfunction in neonatal mice

VK Ninh, EC El Hajj, AJ Mouton, JD Gardner - Cardiovascular toxicology, 2019 - Springer
Fetal alcohol syndrome (FAS) is the most severe condition of fetal alcohol spectrum
disorders (FASD) and is associated with congenital heart defects. However, more subtle …