Objective The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …

Antiretroviral drugs have revolutionized the treatment and prevention of HIV infection;
however, adherence is critical for sustained efficacy. Current HIV treatment consists of three …

Background: Vascular smooth muscle cell (VSMC) phenotypic switching contributes to
cardiovascular diseases. Epigenetic regulation is emerging as a key regulatory mechanism …

There has been a great evolution in the development of coronary stents in order to avoid
both restenosis and thrombosis. Improvements have led to improvements in the design and …

One of the leading causes of morbidity and mortality worldwide is coronary artery disease, a
condition characterized by the narrowing of the artery due to plaque deposits. The standard …

Mechanistic target of rapamycin (mTOR) is the kinase subunit of two structurally and
functionally distinct large multiprotein complexes, referred to as mTOR complex 1 (mTORC1) …

Implanting stents is the most efficient and minimally invasive technique for treating coronary
artery diseases, but the risks of stent thrombosis (ST) and in-stent restenosis (IRS) hamper …

Biodegradable coronary artery stents are sought-after alternatives to permanent stents.
These devices are designed to degrade after the blood vessel heals, leaving behind a …

LARV implants are a promising new technology, but are in early stages of clinical
development. Their potential advantages include more consistent and predictable drug …

Cardiovascular diseases are a pre-eminent global cause of mortality in the modern world.
Typically, surgical intervention with implantable medical devices such as cardiovascular …