Brains are constantly flooded with sensory information that needs to be filtered at the pre-
attentional level and integrated into endogenous activity in order to allow for detection of …

Cognition, memory, and attention and arousal have been linked to nicotinic acetylcholine
receptors (nAChRs). Thus it is not surprising that nAChRs have been strongly implicated as …

BACKGROUND: Difficulty modeling complex behavioral phenotypes in rodents (eg,
language) has hindered pathophysiological investigation and treatment development for …

Reduced N-methyl-D-aspartate-receptor (NMDAR) signaling has been associated with
schizophrenia, autism and intellectual disability. NMDAR-hypofunction is thought to …

Ketamine, an N-methyl-d-aspartate (NMDA) receptor glutamatergic antagonist, has been
studied as a model of schizophrenia when applied in subanesthetic doses. In EEG studies …

Introduction: Electrophysiological responses to auditory stimuli have provided a useful
means of elucidating mechanisms and evaluating treatments in psychiatric disorders …

Electroencephalography (EEG) and related methodologies offer the promise of predicting
the likelihood that novel therapies and compounds will exhibit clinical efficacy early in …

Reduced NMDA‐receptor (NMDAR) function has been implicated in the pathophysiology of
neuropsychiatric disease, most strongly in schizophrenia but also recently in autism …

Background: People with schizophrenia exhibit reduced ability to detect change in the
auditory environment, which has been linked to abnormalities in N-methyl-D-aspartate …

Introduction The prevalence of tobacco use in the population with schizophrenia is
enormously high. Moreover, nicotine dependence is found to be associated with symptom …