A scoping review and meta-analysis of anti-CGRP monoclonal antibodies: predicting response

JB Hong, KS Lange, LH Overeem, P Triller, B Raffaelli… - Pharmaceuticals, 2023 - mdpi.com
Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …

Monoclonal antibodies against calcitonin gene-related peptide for migraine prophylaxis: a systematic review of real-world data

AR Pavelic, C Wöber, F Riederer, K Zebenholzer - Cells, 2022 - mdpi.com
Objective: To perform a systematic review of real-world outcomes for anti-CGRP-mAbs.
Methods: Following the PRISMA guidelines, we searched PubMed for real-world data of …

Long-term effectiveness of three anti-CGRP monoclonal antibodies in resistant chronic migraine patients based on the MIDAS score

LF Iannone, D Fattori, S Benemei, A Chiarugi… - CNS drugs, 2022 - Springer
Background Criteria, including clinical features and effective outcomes, for access and
persistence of novel but costly treatments may vary between countries, thus affecting the …

Maintenance of response and predictive factors of 1‐year GalcanezumAb treatment in real‐life migraine patients in Italy: The multicenter prospective cohort GARLIT …

F Vernieri, N Brunelli, M Marcosano… - European Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose To evaluate the 1‐year effectiveness and tolerability of
galcanezumab in real life and the prognostic indicators of persistent response. Methods …

Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study

K Ihara, S Ohtani, N Watanabe, N Takahashi… - The Journal of …, 2023 - Springer
Background Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) are a
favourable option for patients with migraine who experience distressful headache disability …

The Registry for Migraine (REFORM) study: methodology, demographics, and baseline clinical characteristics

WK Karlsson, H Ashina, CK Cullum… - The Journal of …, 2023 - Springer
Background Erenumab has demonstrated effectiveness for prevention of migraine attacks,
but the treatment is costly, and a considerable proportion of patients do not respond to it. The …

Methodological considerations on real-world evidence studies of monoclonal antibodies against the CGRP-pathway for migraine: a systematic review

N Vandenbussche, K Pisarek, K Paemeleire - The Journal of Headache …, 2023 - Springer
Background Real-world data are accumulating on the effectiveness, tolerability and safety of
anti-calcitonin gene-related peptide pathway monoclonal antibodies for the preventive …

Conversion from chronic to episodic migraine in patients treated with galcanezumab in real life in Italy: the 12-month observational, longitudinal, cohort multicenter …

C Altamura, N Brunelli, M Marcosano, C Aurilia… - Journal of …, 2022 - Springer
Objective To investigate in real-life the conversion from chronic migraine (CM) to episodic
migraine (EM), specifically to EM with High-Frequency (HFEM: 8–14 monthly migraine days …

Detoxification vs non-detoxification before starting an anti-CGRP monoclonal antibody in medication overuse headache

U Pensato, C Baraldi, V Favoni, D Mascarella… - …, 2022 - journals.sagepub.com
Background Medication overuse headache significantly contributes to the chronification
process and treatment refractoriness of migraine. Currently, abrupt discontinuation of the …

Preventive CGRP-targeted therapies for chronic migraine with and without medication-overuse headache

A Alpuente, M Torres-Ferrus, GM Terwindt - Cephalalgia, 2023 - journals.sagepub.com
Background: Calcitonin gene-related peptide (CGRP) targeted therapies are an important
breakthrough in migraine prevention. Randomized clinical trials, post-hoc analyses, and …