Skin in the diagnostics game: Wearable biosensor nano-and microsystems for medical diagnostics

M Dervisevic, M Alba, B Prieto-Simon, NH Voelcker - Nano Today, 2020 - Elsevier
The skin, as the largest and most accessible organ in the human body, contains biofluids
rich in biomarkers useful not only in diagnosis and monitoring of diseases, but also in …

Managing diabetes with hydrogel drug delivery

Y Xiang, B Su, D Liu, MJ Webber - Advanced Therapeutics, 2024 - Wiley Online Library
Diabetes is one of the most pressing healthcare challenges facing society. Dysfunctional
insulin signaling causes diabetes, leading to blood glucose instability and many associated …

Improved pH stability, heat stability, and functionality of phycocyanin after PEGylation

Y Li, Z Zhang, A Abbaspourrad - International Journal of Biological …, 2022 - Elsevier
Abstract Phycocyanin (PC), a spirulina-derived protein–chromophore complex, suffers from
poor techno-functional properties and is highly susceptible to aggregation and color …

[HTML][HTML] Microflow size exclusion chromatography to preserve micromolar affinity complexes and achieve subunit separations for native state mass spectrometry

ES Hecht, EC Obiorah, X Liu, L Morrison… - … of Chromatography A, 2022 - Elsevier
For high throughput native mass spectrometry (MS) protein characterization, it is
advantageous to desalt and separate proteins by size exclusion chromatography (SEC) …

On demand regulation of blood glucose level by biocompatible oxidized starch-Con A nanogels for glucose-responsive release of exenatide

J Bai, H Zhang, Z Yang, P Li, B Liu, D Li, S Liang… - Journal of Controlled …, 2022 - Elsevier
Diabetes mellitus is a long-term chronic disease characterized by abnormal high level blood
glucose (BG). An artificial closed-loop system that mimics pancreatic β-cells and releases …

Lignin Nanoparticles Support Lipase‐Tyrosinase Enzymatic Cascade in the Synthesis of Lipophilic Hydroxytyrosol Ester Derivatives

E Tomaino, E Capecchi, D Piccinino… - ChemCatChem, 2022 - Wiley Online Library
Lipophilic esters of hydroxytyrosol have been synthesized in a one‐pot procedure from
tyrosol and long side‐chain carboxylic acids by a lignin nanoparticles supported enzymatic …

Multitarget sensing of glucose and cholesterol based on Janus hydrogel microparticles

XT Sun, Y Zhang, DH Zheng, S Yue, CG Yang… - Biosensors and …, 2017 - Elsevier
A visualized sensing method for glucose and cholesterol was developed based on the
hemispheres of the same Janus hydrogel microparticles. Single-phase and Janus hydrogel …

A polarity-sensitive far-red fluorescent probe for glucose sensing through skin

L Colvin, D Tu, D Dunlap, A Rios, G Coté - Biosensors, 2023 - mdpi.com
The field of glucose biosensors for diabetes management has been of great interest over the
past 60 years. Continuous glucose monitoring (CGM) is important to continuously track the …

Structural and biochemical analyses of concanavalin A circular permutation by jack bean asparaginyl endopeptidase

SG Nonis, J Haywood, JW Schmidberger… - The Plant …, 2021 - academic.oup.com
Over 30 years ago, an intriguing posttranslational modification was found responsible for
creating concanavalin A (conA), a carbohydrate-binding protein from jack bean (Canavalia …

A layer-by-layer approach to retain a fluorescent glucose sensing assay within the cavity of a hydrogel membrane

AK Locke, AK Means, P Dong, TJ Nichols… - ACS applied bio …, 2018 - ACS Publications
A continuous glucose monitoring device that resides fully in the subcutaneous tissue has the
potential to greatly improve the management of diabetes. Toward this goal, we have …