Copper, an essential trace element that exists in oxidized and reduced forms, has pivotal
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …

Copper (Cu) is an essential micronutrient but excess Cu is potentially toxic. Its important
propensity to cycle between two oxidation states accounts for its frequent presence as a …

Copper is known to trigger endothelial cells towards angiogenesis. Different approaches
have been investigated to develop vascularisation in biomaterials. The angiogenic and …

High costs, long test times, and societal concerns related to animal use have required the
development of in vitro assays for the rapid and cost-effective toxicological evaluation and …

Copper is an essential element in many biological processes. The critical functions
associated with copper have resulted from evolutionary harnessing of its potent redox …

Dithiocarbamates and their complexes with transition metals have been used as common
pesticides, vulcanizing or analytical agents for decades. These compounds are one of the …

Wilson's disease (WD) is a rare, autosomal recessive disorder of copper metabolism caused
by pathogenic mutations in the ATP7B gene. Cellular copper overload is associated with …

The development of new tools for assessing the health of cultured shellfish larvae is crucial
for aquaculture industries to develop and refine hatchery methodologies. We established a …

Background Few studies assessed effects of individual and multiple ions simultaneously on
metabolic outcomes, due to methodological limitation. Methodology/Principal Findings By …

Telomere shortening is a biomarker of cellular senescence and is associated with a wide
range of age-related disease. Oxidative stress is also associated with physiological aging …