Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …

Today, the production and use of various samples of recombinant protein/polypeptide toxins
is known and is actively developing. This review presents state-of-the-art in research and …

Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

This review covers briefly the work carried out at our institute (IBCh), in many cases in
collaboration with other Russian and foreign laboratories, for the last 50 years. It discusses …

Potassium channels are the most diverse group of ion channels in humans. They take vital
parts in numerous physiological processes and their malfunction gives rise to a range of …

Scorpion toxins are well-known as the largest potassium channel peptide blocker family.
They have been successfully proven to be valuable molecular probes for structural research …

Neurotoxins are among the main components of scorpion and snake venoms. Scorpion
neurotoxins affect voltage‐gated ion channels, while most snake neurotoxins target ligand …

Abstract Chimeric potassium channels KcsA-Kv1, which are among the most intensively
studied hybrid membrane proteins to date, were constructed by replacing a part of the pore …

Advanced molecular probes are required to study the functional activity of the Kv1. 2
potassium channel in normal and pathological conditions. To address this, a fully active Kv1 …

Fluorescently labeled peptide blockers of ion channels are useful probes in studying the
localization and functioning of the channels and in the performance of a search for new …