Chemical O‐Glycosylations: An Overview

R Das, B Mukhopadhyay - ChemistryOpen, 2016 - Wiley Online Library
The development of glycobiology relies on the sources of particular oligosaccharides in their
purest forms. As the isolation of the oligosaccharide structures from natural sources is not a …

Recent trends in the synthesis of O-glycosides of 2-amino-2-deoxysugars

AFG Bongat, AV Demchenko - Carbohydrate research, 2007 - Elsevier
The discovery of new methods for stereoselective glycoside synthesis and convergent
oligosaccharide assembly has been critical for the area of glycosciences. At the heart of this …

Oligosaccharide synthesis: from conventional methods to modern expeditious strategies

JT Smoot, AV Demchenko - Advances in Carbohydrate Chemistry and …, 2009 - Elsevier
Although glycoscientists have learned over the years how to isolate certain classes of
naturally occurring complex carbohydrates, the availability of pure natural isolates, remains …

Intramolecular aglycon delivery on polymer support: Gatekeeper monitored glycosylation

Y Ito, T Ogawa - Journal of the American Chemical Society, 1997 - ACS Publications
A novel use of polymer supported glycosyl donor for stereoselective synthesis of β-manno
glycoside is described. This system features the use of polymer support in an …

One‐Pot Synthesis of Sialo‐Containing Glycosyl Amino Acids by Use of an N‐Trichloroethoxycarbonyl‐β‐thiophenyl Sialoside

H Tanaka, M Adachi… - Chemistry–A European …, 2005 - Wiley Online Library
We describe an efficient synthesis of 2, 6‐and 2, 3‐sialyl T antigens linked to serine in a one‐
pot glycosylation. We first investigated the glycosidation of thiosialosides by varying the N …

Methods for modifying human antibodies by glycan engineering

CH Wong, CY Wu - US Patent 10,087,236, 2018 - Google Patents
(57) ABSTRACT 3, 773, 919 A 3, 896, 111 A 4, 137, 230 A 4, 151, 042 A 4, 248, 870 A 4,
256, 746 A 4, 260, 608 A 4, 265, 814 A 4, 270, 537 A 4, 294, 757 A 4, 307, 016 A 4, 308, 268 …

Use of O-glycosylation in total synthesis

H Pellissier - Tetrahedron, 2005 - Elsevier
Carbohydrates are the most abundant group of natural products and the role of sugars as
energy and biosynthetic resources (glycolysis, pentose phosphate cycle, etc.),'energy …

Polyunsaturated C‐glycosidic 4‐hydroxy‐2‐pyrone derivatives: Total synthesis shows that putative orevactaene is likely identical with epipyrone A

J Preindl, S Schulthoff, C Wirtz… - Angewandte Chemie …, 2017 - Wiley Online Library
Orevactaene and epipyrone A were previously thought to comprise the same
polyunsaturated tail but notably different C‐glycosylated 4‐hydroxy‐2‐pyrone head groups …

Compositions and methods for treatment and detection of cancers

CH Wong, TL Hsu, YW Lou, CW Lin, SC Yeh… - US Patent …, 2018 - Google Patents
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that
bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use …

Photoactivatable glycopolymers for the proteome-wide identification of fucose-α (1-2)-galactose binding proteins

A Wibowo, EC Peters… - Journal of the American …, 2014 - ACS Publications
Although fucose-α (1-2)-galactose (Fucα (1-2) Gal)-containing glycans have been implicated
in cognitive processes such as learning and memory, their precise molecular mechanisms …