Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …

ABSTRACT A major focus of current biological studies is to fill the knowledge gaps between
cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical …

Modern biomedical research and preclinical pharmaceutical development rely heavily on
the phenotyping of small vertebrate models for various diseases prior to human testing. In …

In the field of X-ray microcomputed tomography (μCT) there is a growing need to reduce
acquisition times at high spatial resolution (approximate micrometers) to facilitate in vivo and …

Optical coherence tomography (OCT) is a widely used non-invasive biomedical imaging
modality that can rapidly provide volumetric images of samples. Here, we present a deep …

With the explosion of gene editing tools in recent years, there has been a much greater
demand for mouse embryo phenotyping, and traditional methods such as histology and …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

Prenatal alcohol exposure (PAE) can result in a range of anomalies including brain and
behavioral dysfunctions, collectively termed fetal alcohol spectrum disorder. PAE during the …

Cataract is one of the most prevalent causes of blindness around the world. Understanding
the mechanisms of cataract development and progression is important for clinical diagnosis …

Systematic imaging can be broadly defined as the systematic identification and
characterization of biological processes at multiple scales and levels. In contrast to …