Crosstalk of multi-omics platforms with plants of therapeutic importance

D Pandita, A Pandita, SH Wani, SAM Abdelmohsen… - Cells, 2021 - mdpi.com
From time immemorial, humans have exploited plants as a source of food and medicines.
The World Health Organization (WHO) has recorded 21,000 plants with medicinal value out …

Tissue-specific molecular biomarker signatures of type 2 diabetes: an integrative analysis of transcriptomics and protein–protein interaction data

B Calimlioglu, K Karagoz, T Sevimoglu… - Omics: a journal of …, 2015 - liebertpub.com
Type 2 diabetes mellitus is a major global public health burden. A complex metabolic
disease, type 2 diabetes affects multiple different tissues, demanding a “systems medicine” …

Jatropha dioica, an Aztec plant with promising pharmacological properties: A systematic review

A RamÃrez-Moreno… - African Journal of …, 2020 - academicjournals.org
Few pharmacological and toxicological studies have been conducted to demonstrate the
usefulness and safety of using the Jatropha dioica extract. The aim of this study was to …

Designing new kinase inhibitor derivatives as therapeutics against common complex diseases: structural basis of microtubule affinity-regulating kinase 4 (MARK4) …

F Naz, M Shahbaaz, K Bisetty, A Islam… - OMICS: A Journal of …, 2015 - liebertpub.com
Drug development for common complex diseases is in need of new molecular entities and
actionable drug targets. MAP/microtubule affinity-regulating kinase 4 (MARK4) is associated …

Natural products, a potential source of new drugs discovery to combat obesity and diabetes: their efficacy and multi-targets actions in treatment of these diseases

B Dinda, M Dinda - Natural Products in Obesity and Diabetes: Therapeutic …, 2022 - Springer
Since the prehistoric times, at least 60,000 years back as per fossil records, humans have
been using natural products, such as plants, animals, microorganisms, and marine …

Novel Vaccine Candidates against Brucella melitensis Identified through Reverse Vaccinology Approach

US Vishnu, J Sankarasubramanian… - Omics: a journal of …, 2015 - liebertpub.com
Global health therapeutics is a rapidly emerging facet of postgenomics medicine. In this
connection, Brucella melitensis is an intracellular bacterium that causes the zoonotic …

[PDF][PDF] Medicinally important plant Cleome gynandra: a phytochemical and pharmacological explanation

PP Adhikari, SB Paul - Asian Journal of Pharmaceutical and …, 2018 - researchgate.net
Cleome genus includes 601 plant species from the family Cleomaceae. Of more than 600
plants, 206 (34.3%) plants are having accepted species names. Cleome gynandra Linn. is a …

Carica papaya: Potential implications in human health

D Heena, T Sunil - Current Traditional Medicine, 2019 - ingentaconnect.com
Background: Carica papaya, a tree-like herb, is cultivated in more than 50 tropical and
subtropical countries worldwide. The parts [leaves, fruit (ripe and unripe), seeds and latex] …

Repurposing L-menthol for systems medicine and cancer therapeutics? L-menthol induces apoptosis through caspase 10 and by suppressing HSP90

U Faridi, SS Dhawan, S Pal, S Gupta… - Omics: a journal of …, 2016 - liebertpub.com
The objective of the present study was to repurpose L-menthol, which is frequently used in
oral health and topical formulations, for cancer therapeutics. In this article, we argue that …

The Uyghur Population and Genetic Susceptibility to Type 2 Diabetes: Potential Role for Variants in CDKAL1, JAZF1, and IGF1 Genes

M Song, F Zhao, L Ran, M Dolikun, L Wu… - Omics: a journal of …, 2015 - liebertpub.com
Substantial evidence suggests that type 2 diabetes mellitus (T2DM) is a multi-factorial
disease with a strong genetic component. A list of genetic susceptibility loci in populations of …