Increasing evidence indicates that success of targeted therapies in the treatment of cancer is
context-dependent and is influenced by a complex crosstalk between signaling pathways …

Simple Summary As the most common primary liver cancer, HCC is a tricky cancer resistant
to systemic therapies. The fibroblast growth factor family and its receptors are gaining more …

Background: microRNAs (miRNAs) are involved in the progression of Lung adenocarcinoma
(LUAD), however, the functions of miR-6742-5p in LUAD remains unknown, thereby this …

Even though distinctive advances in the field of esophageal cancer therapy have occurred
over the last few years, patients' survival rates remain poor. FGF8, FGF18, and FGFR4 have …

Abstract Brahma-related gene 1 (BRG1), an ATPase subunit of the SWItch/sucrose non-
fermentable (SWI/SNF) chromatin remodeling complex controls multipotent neural crest …

Background Neoadjuvant radiotherapy is a commonly used method for the current standard-
of-care for most patients with rectal cancer, when the effects of radioresistance are limited …

Targeted monotherapies usually fail due to development of resistance by a subgroup of cells
that evolve into recurrent tumors. Alveolar rhabdomyosarcoma is an aggressive myogenic …

Abstract Background Fibroblast growth factors (FGFs) are cell signaling proteins that perform
multiple biological processes in many biological processes (cell development, repair, and …

According to current guidelines, the current treatment for locally advanced rectal cancer is
neoadjuvant therapy, followed by a total mesorectal excision. However, radiosensitivity …

Abstract FGF8, ALK, and EML4 have been identified as promising biomarkers in a number of
malignancies. The aim of this study was to examine the prognostic role of FGF8, ALK, and …