[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

[HTML][HTML] Propolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease: Running title: Propolis against SARS-CoV-2 infection and …

AA Berretta, MAD Silveira, JMC Capcha… - Biomedicine & …, 2020 - Elsevier
Propolis, a resinous material produced by honey bees from plant exudates, has long been
used in traditional herbal medicine and is widely consumed as a health aid and immune …

[HTML][HTML] DNA methylation GrimAge strongly predicts lifespan and healthspan

AT Lu, A Quach, JG Wilson, AP Reiner, A Aviv… - Aging (albany …, 2019 - ncbi.nlm.nih.gov
It was unknown whether plasma protein levels can be estimated based on DNA methylation
(DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful …

[HTML][HTML] Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Molecular biomarkers for vascular cognitive impairment and dementia

S Hosoki, GK Hansra, T Jayasena, A Poljak… - Nature Reviews …, 2023 - nature.com
As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

[HTML][HTML] An aberrant STAT pathway is central to COVID-19

T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2 infection and characterized by diverse clinical
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …

Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility

G Fiorentino, D Cimadomo, F Innocenti… - Human …, 2023 - academic.oup.com
BACKGROUND Folliculogenesis occurs in the highly dynamic environment of the ovary.
Follicle cyclic recruitment, neo-angiogenesis, spatial displacement, follicle atresia and …

[HTML][HTML] Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage

S Deinhardt-Emmer, D Wittschieber, J Sanft… - Elife, 2021 - elifesciences.org
Clinical observations indicate that COVID-19 is a systemic disease. An investigation of the
viral distribution within the human body and its correlation with tissue damage can aid in …

PAI‐1 in tissue fibrosis

AK Ghosh, DE Vaughan - Journal of cellular physiology, 2012 - Wiley Online Library
Fibrosis is defined as a fibroproliferative or abnormal fibroblast activation‐related disease.
Deregulation of wound healing leads to hyperactivation of fibroblasts and excessive …

Coronavirus disease 2019–associated coagulopathy

G Lippi, F Sanchis-Gomar, EJ Favaloro, CJ Lavie… - Mayo Clinic …, 2021 - Elsevier
Patients with the severe form of coronavirus disease 2019 (COVID-19) have been frequently
found to suffer from both arterial and venous thrombotic events due to the perpetuation of a …