Recent advances of oral film as platform for drug delivery

M He, L Zhu, N Yang, H Li, Q Yang - International Journal of Pharmaceutics, 2021 - Elsevier
Orally drug delivery film has received extensive interest duo to a distinct set of its
advantageous properties compared to the traditional orally administered dosages, including …

[HTML][HTML] Orodispersible films—Current state of the art, limitations, advances and future perspectives

J Ferlak, W Guzenda, T Osmałek - Pharmaceutics, 2023 - mdpi.com
Orodispersible Films (ODFs) are drug delivery systems manufactured with a wide range of
methods on a big scale or for customized medicines and small-scale pharmacy. Both ODFs …

In vitro and in vivo evaluation of gellan gum hydrogel films: Assessing the co impact of therapeutic oils and ofloxacin on wound healing

H Mahmood, IU Khan, M Asif, RU Khan… - International Journal of …, 2021 - Elsevier
Herein, we report co-encapsulation of ofloxacin with tea tree or lavender oil in gellan gum
based hydrogel films by solvent casting ionotropic gelation method as wound dressing …

[HTML][HTML] Orodispersible films: current innovations and emerging trends

S Jacob, SHS Boddu, R Bhandare, SS Ahmad, AB Nair - Pharmaceutics, 2023 - mdpi.com
Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that
are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic …

[HTML][HTML] The Potential of Films as Transmucosal Drug Delivery Systems

ACW de Carvalho, NF Paiva, IK Demonari, MPF Duarte… - Pharmaceutics, 2023 - mdpi.com
Pharmaceutical films are polymeric formulations used as a delivery platform for
administration of small and macromolecular drugs for local or systemic action. They can be …

[Retracted] Ameliorated Stomach Specific Floating Microspheres for Emerging Health Pathologies Using Polymeric Konjac Glucomannan‐Based Domperidone

JMM Mohamed, N Mahajan… - BioMed Research …, 2022 - Wiley Online Library
The goal of this study was to use polymeric konjac glucomannan (KGM), Kollidon VA 64
(KVA64), and glutaraldehyde to ameliorate stomach specific floating microspheres (SSFM) …

[HTML][HTML] Three-Dimensional-Printed Oral Films Based on LCD: Influence Factors of the Film Printability and Received Qualities

T Xu, H Li, Y Xia, S Ding, Q Yang, G Yang - Pharmaceutics, 2023 - mdpi.com
As an oral mucosal drug delivery system, oral films have been of wide concern in recent
years because of their advantages such as rapid absorption, being easy to swallow and …

Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and …

A Zafar, M Afzal, AM Quazi, M Yasir, I Kazmi… - Journal of Drug Delivery …, 2021 - Elsevier
The strategies to avoid the first-pass metabolism via nose to systemic pathway are been
explored to improve the bioavailability of the therapeutic agents. The present study aimed to …

Prediction of enhanced drug solubility related to clathrate compositions and operating conditions: Machine learning study

C Wang, Y Cheng, Y Ma, Y Ji, D Huang… - International Journal of …, 2023 - Elsevier
Although complexation technique has been documented as a promising strategy to enhance
the dissolution rate and bioavailability of water-insoluble drugs, prediction of the enhanced …

[HTML][HTML] Design and development of sublingual printlets containing domperidone nanocrystals using 3D melting solidification printing process (MESO-PP)

L Lopez-Vidal, AJ Paredes, SD Palma, JP Real - Pharmaceutics, 2023 - mdpi.com
Domperidone (DOM) is a drug commonly used to treat nausea and vomiting, as well as
gastrointestinal disorders. However, its low solubility and extensive metabolism pose …