Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause
of sexually transmitted infections and the etiologic agent of trachoma, which is the leading …

Chlamydia trachomatis serovars are obligate intracellular bacterial pathogens mainly
causing ocular and urogenital infections that affect millions of people worldwide and which …

Bacterial pathogens have developed complex strategies to successfully survive and
proliferate within their hosts. Throughout the infection cycle, direct interaction with host cells …

As an obligate intracellular pathogen, host cell invasion is paramount to Chlamydia
trachomatis proliferation. While the mechanistic underpinnings of this essential process …

The actin cytoskeleton is crucially important to maintenance of the cellular structure, cell
motility, and endocytosis. Accordingly, bacterial pathogens often co-opt the actin …

Chlamydia trachomatis is the leading cause of infectious blindness and a sexually
transmitted infection. All chlamydiae are obligate intracellular bacteria that replicate within a …

Chlamydia invasion of epithelial cells is a pathogen-driven process involving two
functionally distinct effectors–TarP and TmeA. They collaborate to promote robust actin …

Focal adhesions (FAs) serve as dynamic signaling hubs within the cell. They connect
intracellular actin to the extracellular matrix (ECM) and respond to environmental cues. In …

The lifestyle of Chlamydiae is unique: the bacteria alternate between two morphologically
distinct forms, an infectious non-replicative elementary body (EB), and a replicative, non …

Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that thrives in the
inflamed environment of the gingival crevice, and is strongly associated with periodontal …